Evidence map›Paper›PMID 37326711›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Mass Spectrometry-Based Vitreous Proteomics: Validated Methods and Analysis Pipeline.

Sarah Weber, Nick Carruthers, Chris Gates, Yuanjun Zhao, Jeffrey Sundstrom

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
6.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sarah WeberDepartment of Ophthalmology, Penn State College of Medicine, Hershey, PA, USA.
Nick CarruthersBioinformatics Core, Biomedical Research Core Facilities, University of Michigan Medical School, Ann Arbor, MI, USA.
Chris GatesBioinformatics Core, Biomedical Research Core Facilities, University of Michigan Medical School, Ann Arbor, MI, USA.
Yuanjun ZhaoDepartment of Ophthalmology, Penn State College of Medicine, Hershey, PA, USA.
Jeffrey SundstromDepartment of Ophthalmology, Penn State College of Medicine, Hershey, PA, USA. jsundstrom@pennstatehealth.psu.edu.
Penn State Milton S. Hershey Medical Center · USUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal diseases like diabetic retinopathy and age-related macular degeneration affect millions of individuals worldwide and often lead to vision loss. Vitreous fluid abuts the retina, is accessible for sampling, and contains many proteins related to retinal disease. Therefore, analysis of vitreous is an important tool for studying retinal disease. Because it is rich in proteins and extracellular vesicles, mass spectrometry-based proteomics is an excellent method for vitreous analysis. Here, we discuss important variables to consider when performing vitreous proteomics via mass spectrometry.

Indexed as

Diabetic RetinopathyProteomicsHumansMass SpectrometryRetinaVitreous BodyExtracellular vesiclesMass spectrometryProteomicsRetinal diseaseVitreous

Identifiers

PMID37326711
OpenAlexW4380872044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.