Evidence map›Paper›PMID 37326306›Full record

ArticleeLife2023

An extracellular vesicle targeting ligand that binds to Arc proteins and facilitates Arc transport in vivo.

Peter H Lee, Michael Anaya, Mark S Ladinsky, Justin M Reitsma, Kai Zinn

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Extracellular vesicles inEXO : beyond the cell · 2026
    Article
  4. Review
  5. "Arc - A viral vector of memory and synaptic plasticity".Current opinion in neurobiology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter H LeeDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0003-2411-6094
Michael AnayaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Mark S LadinskyDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0002-1036-3513
Justin M ReitsmaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Kai ZinnDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0002-6706-5605

Funding

MOLECULAR GENETICS OF DROSOPHILA CNS DEVELOPMENTR01NS028182 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Engin Ozkan, KAI G ZINN · 1990 to 2026
$7.3M
Molecular Genetics of CNS DevelopmentR37NS028182 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ZINN, KAI G · 2014 to 2020
$3.3M
Regulation of synaptic targeting in the Drosophila larval neuromuscular system by immunoglobulin superfamily cell surface proteinsR01NS096509 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ZINN, KAI G · 2016 to 2020
$1.8M
NINDS NIH HHS NS096509NINDS NIH HHS NS28182NINDS NIH HHS R01 NS028182NINDS NIH HHS R01 NS096509NINDS NIH HHS R37 NS028182
6 · The paper itself

Abstract

Communication between distant cells can be mediated by extracellular vesicles (EVs) that deliver proteins and RNAs to recipient cells. Little is known about how EVs are targeted to specific cell types. Here, we identify the

Indexed as

Drosophila ProteinsExtracellular VesiclesAnimalsDrosophilaLigandsMammalsMembrane ProteinsRNA, MessengerDrosophila ProteinsLigandsMembrane ProteinsRNA, Messengeramyloid precursor proteincapsidcell biologyD. melanogasterexosomeextracellular vesicleprotein transportretrotransposon

Identifiers

PMID37326306
PMCPMC10289811

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.