ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2023
Prognostic impact of morphology and duration of premature ventricular contractions in a population without structural heart disease.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 3 citations in OpenAlex.
- Long-term survival in patients with premature ventricular complexes and no structural heart disease.Open heart · 2026Observational
- The Clinical Role of Electrocardiographic Morphology of Premature Ventricular Contractions for Prognostic Outcomes in Children.Medicina (Kaunas, Lithuania) · 2026Observational
- Comprehensive cardiac magnetic resonance imaging in patients with idiopathic premature ventricular contractions: role of feature-tracking strain and T1/T2 mapping in detecting subclinical myocardial dysfunction.Quantitative imaging in medicine and surgery · 2026Article
- Association between systemic immune-inflammation index and ventricular premature contractions in patients without structural heart disease.Frontiers in cardiovascular medicine · 2026Article
- The Impact of the Spatial Distribution of Ventricular Extrasystoles on Implantable Cardioverter-Defibrillator Recipients.Pacing and clinical electrophysiology : PACE · 2025Article
- Prognostic impact of morphology and duration of premature ventricular contractions in a population without structural heart disease.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundPremature ventricular contractions (PVCs) are a common form of arrhythmia associated with an unfavorable prognosis in patients with structural heart disease. It is unclear whether PVCs site of origin and QRS-width has a prognostic significance in patients without structural heart disease. The aim of this study was to assess the prognostic importance of PVCs morphology and duration in this patient group.
methodsWe included 511 consecutive patients without a history of previous heart disease. They were examined with echocardiography and exercise test with normal findings. We categorized the PVCs from a 12 lead ECG according to morphology and width of the QRS-complex and analyzed the outcome in terms of a composite endpoint of total mortality and cardiovascular morbidity.
resultsDuring a median follow-up time of 5.3 years, 19 patients (3.5%) died and 61 (11.3%) met the composite outcome. Patients with PVCs originating from the outflow tracts had a significantly lower risk for the composite outcome compared to patients with non-OT-PVCs. Similarly, patients with PVC originating from the right ventricle had a better outcome than patients with left ventricular PCVs. No difference in outcome depending on QRS-width during PVCs was noticed.
conclusionIn our cohort of consecutively included PVC patients without structural heart disease PVCs from the outflow tracts were associated with a better prognostic outcome than non-OT PVCs; the same was true for right ventricular PVCs when compared to left ventricular ones. The classification of the origin of the PVCs was based on 12-lead ECG morphology. QRS-width during PVC did not seem to have prognostic significance.
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