Evidence map›Paper›PMID 37326276›Full record

ArticleActa bio-medica : Atenei Parmensis2023

Histological and clinical analysis of knee cyclops lesions.

Giuseppe Aloisi, Remo Goderecci, Andrea Fidanza, Gianluca Cipolloni, Vittorio Calvisi

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In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Giuseppe Aloisia:1:{s:5:"en_US";s:37:"Università degli studi dell'Aquila";}. galoisidr@gmail.com.
Remo GoderecciGiuseppe Mazzini Civil Hospital, ASL 4 Teramo. remogoderecci@gmail.com.
Andrea Fidanza. andrea.fidanza@graduate.univaq.it.
Gianluca CipolloniSan Camillo De' Lellis Hospital, Rieti. g.cipolloni@aslrieti.it.
Vittorio CalvisiUniversity of L'Aquila. vittorio.calvisi@univaq.it.
University of L'Aquila · ITEllis Hospital · USFlint Institute Of Arts · USNini Hospital · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimCyclops Syndrome, first described by Jackson and Schaefer in 1990, is known as a complication of anterior cruciate ligament reconstruction (ACLR). However further researches have demonstrated that cyclops can be present even without symptoms and/or in absence of ACLR, simply configuring itself as a lesion in patients with rupture of the native ligament.

methodsThis is a retrospective cohort study in which we report our experience of 13 cyclops lesions found between 126 patients during a primary arthroscopic ACLR. Preoperative examination with tests of joint stability and range of movement measurement was performed and recorded. Accurate joint examination was performed during arthroscopy and the cyclops lesions found were removed and analyzed with haematoxylin-eosin coloration. Post-operative clinical examination was performed until 6 months of follow-up.

resultsHistological analysis showed proliferation of dense fibroelastic polypoid nodules with a macroscopically histological aspects of a "blue eye", hence the name Cyclops. At 6 months of follow-up after surgery, none of the patients reported pain at terminal extension or instability and they were all able to resume their previous activities.

conclusionsOur study confirmed that surgical reconstruction of the ACL is not the only condition in which the Cyclops Syndrome develops; in fact our histological analysis indicate that the Cyclops lesions develop like a reactive fibroproliferative process following the rupture of the native ACL fibers, as scar reaction to the trauma: for this reason an accurate arthroscopic detection of these Cyclops lesions is crucial during primary ACL reconstruction in order to obtain the best surgical outcomes.

Indexed as

Anterior Cruciate LigamentAnterior Cruciate Ligament InjuriesArthroscopyHumansKnee JointMinocyclineRetrospective StudiesSyndromeMinocycline

Identifiers

PMID37326276
PMCPMC10308458
OpenAlexW4380871827

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.