Evidence map›Paper›PMID 37326220›Full record

ReviewClinical and translational science2023

Anticoagulant therapy in COVID-19: A narrative review.

Zeinab Mohseni Afshar, Ali Tavakoli Pirzaman, Rezvan Hosseinzadeh, Arefeh Babazadeh, Mohamad Ali Taghizadeh Moghadam, Seyed Rouhollah Miri, Terence T Sio, Mark J M Sullman, Mohammad Barary, Soheil Ebrahimpour

Open access · goldAbstract readReview
In one paragraph

Review in Clinical and translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Unveiling the Link Between COVID-19 and Pulmonary Hypertension.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  3. Review
  4. Stroke, infections, and New Mechanisms: a Narrative Review.Current neurology and neuroscience reports · 2025
    Review
  5. Review
  6. Review
  7. COVID-19: a vascular nightmare unfolding.Frontiers in immunology · 2025
    Review
  8. Review
  9. Review
  10. Anticoagulant therapy in COVID-19: A narrative review.Clinical and translational science · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Zeinab Mohseni AfsharClinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.ORCID 0000-0002-1085-374X
Ali Tavakoli PirzamanStudent Research Committee, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0002-9426-7034
Rezvan HosseinzadehStudent Research Committee, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0001-9399-3854
Arefeh BabazadehInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0002-1362-7203
Mohamad Ali Taghizadeh MoghadamStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyed Rouhollah MiriCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.ORCID 0000-0002-1403-977X
Terence T SioDepartment of Radiation Oncology, Mayo Clinic, Phoenix, Arizona, USA.ORCID 0000-0003-4210-5479
Mark J M SullmanDepartment of Social Sciences, University of Nicosia, Nicosia, Cyprus.ORCID 0000-0001-7920-6818
Mohammad BararyStudent Research Committee, Virtual School of Medical Education and Management, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-8733-9370
Soheil EbrahimpourInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.ORCID 0000-0003-3204-0448
Babol University of Medical Sciences · IRKermanshah University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRShiraz University of Medical Sciences · IRUniversity of Nicosia · CYUniversity of Tehran · IRWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can manifest itself in several ways, including coagulopathy and thrombosis. These complications can be the first and sometimes only manifestations of SARS-CoV-2 infection and can occur early or late in the course of the disease. However, these symptoms are more prevalent in hospitalized patients with venous thromboembolism, particularly those admitted to intensive care units. Moreover, various forms of arterial and venous thrombosis, or micro- or macro-vasculature embolisms, have been reported during the current pandemic. They have led to harmful consequences, such as neurological and cardiac events, nearly all resulting from the hypercoagulable state caused by this viral infection. The severe hypercoagulability observed in patients with COVID-19 accounts for most cases of the disease that become critical. Therefore, anticoagulants seem to be one of the most vital therapeutics for treating this potentially life-threatening condition. In the current paper, we present a thorough review of the pathophysiology of COVID-19-induced hypercoagulable state and the use of anticoagulants to treat SARS-CoV-2 infections in different patient groups, as well as their pros and cons.

Indexed as

Blood Coagulation DisordersCOVID-19ThrombosisAnticoagulantsHumansSARS-CoV-2Anticoagulants

Identifiers

PMID37326220
PMCPMC10499427
OpenAlexW4380870116

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.