Evidence map›Paper›PMID 37326031›Full record

ArticleMolecular medicine reports2023

A pH‑responsive hyaluronic acid nano‑vehicle co‑encapsulating doxorubicin and all‑trans retinoic acid for the inhibition of hepatic stellate cell‑induced tumor growth and metastasis.

Qiao Lu, Xueyang Gong, Guangtao Jia, Jingliang Wu, Siwei Liu, Ke Song, Guixiang Tian

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qiao Lu *Department of Life Science and Technology, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Xueyang Gong *Department of Life Science and Technology, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Guangtao Jia *Department of Life Science and Technology, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Jingliang WuDepartment of Nursing, Weifang University of Science and Technology, Weifang, Shandong 262700, P.R. China.
Siwei LiuDepartment of Life Science and Technology, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Ke SongDepartment of Life Science and Technology, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Guixiang TianDepartment of Life Science and Technology, Weifang Medical University, Weifang, Shandong 261053, P.R. China.
Weifang Medical University · CNWeifang University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All‑trans retinoic acid (ATRA) has been implicated in the differentiation of hepatic stellate cells (HSCs). In the present study, the liver‑targeting hyaluronic acid micelles (ADHG) were prepared for co‑delivery of ATRA and doxorubicin (DOX) to block the HSC‑hepatoma interrelation. To simulate the tumor microenvironment, an

Indexed as

Carcinoma, HepatocellularHyaluronic AcidAnimalsDoxorubicinHepatic Stellate CellsHydrogen-Ion ConcentrationMiceTretinoinTumor MicroenvironmentDoxorubicinHyaluronic AcidTretinoinall‑trans retinoic acidanti‑hepatomacombination therapyhepatic stellate cells

Identifiers

PMID37326031
PMCPMC10308492
OpenAlexW4380081893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.