ArticleStroke2023
Personality and Risk of Incident Stroke in 6 Prospective Studies.
Article in Stroke, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Meta-analysis of Early Risk Factors Associated with Cerebrovascular Diseases.Current neurovascular research · 2026Pooled it
- Personality and cardiovascular mortality risk: a multi-cohort analysis in individuals with and without pre-existing cardiovascular disease.Journal of behavioral medicine · 2025Pooled it
- Personality and Risk of Arthritis in Six Longitudinal Samples.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Pooled it
- Trait impulsivity and risk of cardiovascular disease over 8 years: results from the NutriNet-Santé cohort.European journal of epidemiology · 2026Article
- Clinical, cognitive and neuropsychiatric correlates of personality in Wilson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Trends over 45 years in personality traits among older populations.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Personality and epigenetic aging: A multi-cohort and multi-clock study.Psychoneuroendocrinology · 2025Article
- Research Progress on the Pathogenesis of Post-Stroke Depression.ACS omega · 2025Review
- Relationship between personality and poststroke functional outcomes: a systematic review.BMJ neurology open · 2025Article
- Neuroticism, loneliness, all-cause and cause-specific mortality: A 17-year study of nearly 500,000 individuals.Journal of affective disorders · 2025Article
- The mediational role of hearing acuity in the association between personality and memory: Evidence from the health and retirement study and the English Longitudinal Study of Ageing.Journal of psychosomatic research · 2024Article
- Physical, cognitive, and social activities as mediators between personality and cognition: evidence from four prospective samples.Aging & mental health · 2024Article
- Personality traits and the risk of sensory impairment: Evidence from the National Health and Aging Trends Study.Journal of psychosomatic research · 2023Article
- Neuroticism and white matter hyperintensities.Journal of psychiatric research · 2023Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundA large literature has examined a broad range of factors associated with increased risk of stroke. Few studies, however, have examined the association between personality and stroke. The present study adopted a systematic approach using a multi-cohort design to examine the associations between 5-Factor Model personality traits (neuroticism, extraversion, openness, agreeableness, and conscientiousness) and incident stroke using data from 6 large longitudinal samples of adults.
methodsParticipants (age range: 16-104 years old, N=58 105) were from the MIDUS (Midlife in the United States) Study, the HRS (Health and Retirement Study), The US (Understanding Society) study, the WLS (Wisconsin Longitudinal Study), the NHATS (National Health and Aging Trends Study), and the LISS (Longitudinal Internet Studies for the Social Sciences). Personality traits, demographic factors, clinical and behavioral risk factors were assessed at baseline; stroke incidence was tracked over 7 to 20 years follow-up.
resultsMeta-analyses indicated that higher neuroticism was related to a higher risk of incident stroke (hazard ratio, 1.15 [95% CI, 1.10-1.20];
conclusionsSimilar to other cardiovascular and neurological conditions, higher neuroticism is a risk factor for stroke incidence, whereas higher conscientiousness is a protective factor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.