Evidence map›Paper›PMID 37325874›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB.

Yaoyao Yan, Qi Lv, Feilong Zhou, Yujie Jian, Liu Xinhua, Xing Chen, Yong Hu

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Effects of α-terpineol and 1,8-cineole fromFrontiers in veterinary science · 2026
    Article
  2. Review
  3. Anti-Inflammatory Effects ofCurrent issues in molecular biology · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yaoyao YanSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei, PR China.
Qi LvSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei, PR China.
Feilong ZhouSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei, PR China.
Yujie JianSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei, PR China.
Liu XinhuaSchool of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Medical University, Hefei, PR China.ORCID 0000-0002-7984-2977
Xing ChenSchool of Public Health, Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Hefei, PR China.ORCID 0000-0001-8558-4743
Yong HuAnhui Academy of Agricultural Sciences, Agricultural Products Processing Institute, Hefei, P. R. China.
Anhui Medical University · CNAnhui Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, based on the effect of compounds on the activation of NF-κB and NO release, compound

Indexed as

NF-kappa BTumor Necrosis Factor-alphaAnti-Inflammatory AgentsHumansInflammationInterleukin-6LipopolysaccharidesAnti-Inflammatory AgentsInterleukin-6LipopolysaccharidesNF-kappa BTumor Necrosis Factor-alphaanti-inflammation small moleculeLPS-induced inflammationNF-κB pathwayNO

Identifiers

PMID37325874
PMCPMC10281321
OpenAlexW4380871102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.