Evidence map›Paper›PMID 37325748›Full record

ArticleFrontiers in psychology2023

Repeatability and comparison of 2D and 4D flow MRI measurement of intracranial blood flow and pulsatility in healthy individuals and patients with cerebral small vessel disease.

Alasdair G Morgan, Michael J Thrippleton, Michael Stringer, Ning Jin, Joanna M Wardlaw, Ian Marshall

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Alasdair G MorganCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Michael J ThrippletonCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Michael StringerCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Ning JinSiemens Medical Solutions USA, Inc., Cleveland, OH, United States.
Joanna M WardlawCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Ian MarshallCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
UK Dementia Research Institute · GBUniversity of Edinburgh · GBSiemens (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: While 2D phase-contrast MRI is often used to examine intracranial vessels in neurovascular disease contexts, the ability of 4D flow to assess many vessels at once makes it an attractive alternative. We aimed to assess the repeatability, reliability, and conformity of 2D and 4D flow across intracranial vessels. Methods: Using correlation analyses and paired Results: Repeatability for PI measurements was mostly classed as good using both 2D (median ICC = 0.765) and 4D (0.772) methods, and for mean flow was mostly moderate across both (2D: 0.711, 4D: 0.571). 4D reliability was good for PI (0.877-0.906) and moderate for mean flow (0.459-0.723). Arterial PI measurements were generally higher using the 2D method, while mean flow was mostly higher using 4D flow. Discussion: These results imply that PI measurement using 4D flow is repeatable and reliable across intracranial arteries and veins, but care should be paid to absolute flow measurements as they are susceptible to variation depending on slice placement, resolution, and lumen segmentation practices.

Indexed as

4D flowflow imagingintracranial vesselsMRIphase-contrastpulsatility

Identifiers

PMID37325748
PMCPMC10262051
OpenAlexW4380871975

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.