Evidence map›Paper›PMID 37325632›Full record

ReviewFrontiers in immunology2023

New insights into inflammatory memory of epidermal stem cells.

Dapeng Cheng, Xiaochen Zhu, Shaochen Yan, Linli Shi, Zhi Liu, Xin Zhou, Xinling Bi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Epithelial-Dermal Immune Memory: TrackingInternational journal of molecular sciences · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. CD38bioRxiv : the preprint server for biology · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Molecular chaos under the skin: Epigenetic reprogramming in hidradenitis suppurativa.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dapeng ChengDepartment of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Xiaochen ZhuDepartment of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Shaochen YanDepartment of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Linli ShiDepartment of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Zhi LiuDepartment of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Xin ZhouDepartment of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Xinling BiDepartment of Dermatology, Changhai Hospital, Naval Medical University, Shanghai, China.
Second Military Medical University · CNChanghai Hospital · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory memory, as one form of innate immune memory, has a wide range of manifestations, and its occurrence is related to cell epigenetic modification or metabolic transformation. When re-encountering similar stimuli, executing cells with inflammatory memory function show enhanced or tolerated inflammatory response. Studies have identified that not only hematopoietic stem cells and fibroblasts have immune memory effects, but also stem cells from various barrier epithelial tissues generate and maintain inflammatory memory. Epidermal stem cells, especially hair follicle stem cells, play an essential role in wound healing, immune-related skin diseases, and skin cancer development. In recent years, it has been found that epidermal stem cells from hair follicle can remember the inflammatory response and implement a more rapid response to subsequent stimuli. This review updates the advances of inflammatory memory and focuses on its mechanisms in epidermal stem cells. We are finally looking forward to further research on inflammatory memory, which will allow for the development of precise strategies to manipulate host responses to infection, injury, and inflammatory skin disease.

Indexed as

Hair FollicleWound HealingEpidermal CellsSkinStem Cellschromatin accessibilityepidermal stem cellsepigenetic memoryhair follicular bulgeinflammatory memory

Identifiers

PMID37325632
PMCPMC10264694
OpenAlexW4378901067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.