Evidence map›Paper›PMID 37325554›Full record

ReviewFrontiers in cell and developmental biology2023

FGF signaling in cranial suture development and related diseases.

Xiaolei Zhao, Shannon Erhardt, Kihan Sung, Jun Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Role of FGF2 in promoting osteogenic differentiation for craniofacial bone regeneration.Regenerative engineering and translational medicine · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Overexpression ofFrontiers in cell and developmental biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xiaolei ZhaoDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Shannon ErhardtDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Kihan SungDepartment of BioSciences, Rice University, Houston, TX, United States.
Jun WangDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
The University of Texas MD Anderson Cancer Center · USRice University · USThe University of Texas Health Science Center at Houston · US

Funding

Molecular Regulatory Mechanism of Cranial Neural Crest DevelopmentR01DE029014 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WANG, JUN · 2020 to 2024
$1.8M
A Hippo-Yap Pathway in Cranial Bone Development and RegenerationK01DE026561 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WANG, JUN · 2017 to 2021
$739k
NIDCR NIH HHS K01 DE026561NIDCR NIH HHS R01 DE029014
6 · The paper itself

Abstract

Suture mesenchymal stem cells (SMSCs) are a heterogeneous stem cell population with the ability to self-renew and differentiate into multiple cell lineages. The cranial suture provides a niche for SMSCs to maintain suture patency, allowing for cranial bone repair and regeneration. In addition, the cranial suture functions as an intramembranous bone growth site during craniofacial bone development. Defects in suture development have been implicated in various congenital diseases, such as sutural agenesis and craniosynostosis. However, it remains largely unknown how intricate signaling pathways orchestrate suture and SMSC function in craniofacial bone development, homeostasis, repair and diseases. Studies in patients with syndromic craniosynostosis identified fibroblast growth factor (FGF) signaling as an important signaling pathway that regulates cranial vault development. A series of

Indexed as

cranial suturecraniosynostosisFGF signalingneural crestrepairsuture mesenchymal stem cell

Identifiers

PMID37325554
PMCPMC10267317
OpenAlexW4379053808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.