Evidence map›Paper›PMID 37325398›Full record

ArticleJACC. Basic to translational science2023

Dietary Effects on Monocyte Phenotypes in Subjects With Hypertriglyceridemia and Metabolic Syndrome.

Zeqin Lian, Xiao-Yuan Dai Perrard, Antu Kalathookunnel Antony, Xueying Peng, Lu Xu, Jing Ni, Bingqian Zhang, Veronica O'Brien, Anum Saeed, Xiaoming Jia and 7 more

Registry-linked trialAbstract read
In one paragraph

Article in JACC. Basic to translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03591588 (Effects of Diet Interventions on Monocyte Phenotypes in Individuals With Metabolic Syndrome), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03591588 nacompletednot on this map

Effects of Diet Interventions on Monocyte Phenotypes in Individuals With Metabolic Syndrome

TypeinterventionalSponsorBaylor College of MedicineRan2016 to 2020Enrolled20ConditionsMetabolic Syndrome, HypertriglyceridemiaArmsdiet
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Inflammatory Effects of Triglycerides: Relevant or Redundant?JACC. Basic to translational science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Zeqin LianDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Xiao-Yuan Dai PerrardDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Antu Kalathookunnel AntonyDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Xueying PengDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Lu XuDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Jing NiDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Bingqian ZhangDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Veronica O'BrienDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Anum SaeedDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Xiaoming JiaDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Aliza HussainDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Bing YuDepartment of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center, Houston, Texas, USA.
Scott I SimonDepartment of Biomedical Engineering, University of California, Davis, California, USA.
Frank M SacksDepartment of Nutrition, Harvard T.H. Chan School of Public Health, and Department of Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, Massachusetts, USA.
Ron C HoogeveenDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Christie M BallantyneDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Huaizhu WuDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.

Funding

Monocyte Activation and the Role of CD11c in obesity-linked metabolic syndromeR01HL098839 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI WU, HUAIZHU · 2010 to 2019
$3.2M
Inflammation and insulin resistance in agingR01AG065197 · NIA · BAYLOR COLLEGE OF MEDICINE · PI Huaizhu Wu · 2022 to 2026
$2.0M
Regulation of Type 1 Inflammation in Diet-induced ObesityR01DK121348 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI WU, HUAIZHU · 2020 to 2023
$1.6M
NHLBI NIH HHS R01 HL098839NIA NIH HHS R01 AG065197NIDDK NIH HHS R01 DK121348
6 · The paper itself

Abstract

In patients with hypertriglyceridemia, a short-term low-saturated fat vs high-saturated fat diet induced lower plasma lipids and improved monocyte phenotypes. These findings highlight the role of diet fat content and composition for monocyte phenotypes and possibly cardiovascular disease risk in these patients. (Effects of Dietary Interventions on Monocytes in Metabolic Syndrome; NCT03591588).

Indexed as

ASCVDhigh saturated fat diethypertriglyceridemialow saturated fat dietmonocyte

Identifiers

PMID37325398
PMCPMC10264566

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.