Riboswitches, from cognition to transformation.

Jingdong Xu, Junyuan Hou, Mengnan Ding, Zhiwen Wang, Tao Chen

Open access · goldAbstract readReview

In one paragraph

Review in Synthetic and systems biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.5field-weighted citation impact, top 33% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jingdong XuSchool of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, China.

Junyuan HouSchool of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, China.

Mengnan DingSchool of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, China.

Zhiwen WangSchool of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, China.

Tao ChenSchool of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, China.

Ministry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Riboswitches are functional RNA elements that regulate gene expression by directly detecting metabolites. Twenty years have passed since it was first discovered, researches on riboswitches are becoming increasingly standardized and refined, which could significantly promote people's cognition of RNA function as well. Here, we focus on some representative orphan riboswitches, enumerate the structural and functional transformation and artificial design of riboswitches including the coupling with ribozymes, hoping to attain a comprehensive understanding of riboswitch research.

Indexed as

ApplicationsAptazymesGene regulatory elementsLigand diversityRiboswitchesStructural transformation

Identifiers

PMID37325181

DOI10.1016/j.synbio.2023.05.008

PMCPMC10265488

OpenAlexW4379260979

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.