Evidence map›Paper›PMID 37324745›Full record

ArticleFrontiers in nutrition2023

Low body mass index is associated with diminished plasma cytokines and chemokines in both active and latent tuberculosis.

Nathella Pavan Kumar, Arul P Nancy, Kadar Moideen, Pradeep A Menon, Vaithilingam V Banurekha, Dina Nair, Sujatha Nott, Subash Babu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Body Mass Index and Incident Tuberculosis in Close Tuberculosis Contacts.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Nathella Pavan KumarICMR-National Institute for Research in Tuberculosis, Chennai, India.
Arul P NancyNIAID - International Center for Excellence in Research, Chennai, India.
Kadar MoideenNIAID - International Center for Excellence in Research, Chennai, India.
Pradeep A MenonICMR-National Institute for Research in Tuberculosis, Chennai, India.
Vaithilingam V BanurekhaICMR-National Institute for Research in Tuberculosis, Chennai, India.
Dina NairICMR-National Institute for Research in Tuberculosis, Chennai, India.
Sujatha NottInfectious Diseases, Dignity Health, Chandler, AZ, United States.
Subash BabuNIAID - International Center for Excellence in Research, Chennai, India.
National Institute of Research in Tuberculosis · INInternational Centers for Excellence in Research · INDignity Health · USNational Institute on Drug Abuse · US

Funding

India International Center for Excellence in ResearchZIAAI001065 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2025
$19.0M
6 · The paper itself

Abstract

Introduction: Low body mass index (BMI) is a major risk factor for tuberculosis (PTB). Low BMI can impair the immune system and thus might affect TB incidence. Methods: We examined the plasma levels of Type 1, Type 17, pro-inflammatory, Type 2 and regulatory cytokines and CC and CXC chemokines in PTB and latent TB (LTB) individuals with low BMI (LBMI) or normal BMI (NBMI). Results: Our data show that PTB is associated with significantly lower levels of IFN Conclusion: Thus, LBMI has a major impact on the cytokine and chemokine milieu of both PTB and LTB and might predispose to the increased risk of tuberculosis by this immunomodulatory effect.

Indexed as

body mass indexchemokinescytokineslatent tuberculosistuberculosis

Identifiers

PMID37324745
PMCPMC10265642
OpenAlexW4378906814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.