Evidence map›Paper›PMID 37324738›Full record

ReviewFrontiers in nutrition2023

Flavonoids improve type 2 diabetes mellitus and its complications: a review.

Xinrui Yi, Mosi Dong, Naifei Guo, Jinlong Tian, Ping Lei, Song Wang, Yufeng Yang, Yan Shi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 89 citations in OpenAlex.

  1. SuFEx-Enabled Reprogramming of Flavonoids for Selective α-Glucosidase Covalent Inhibition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Investigating a newBiotechnology reports (Amsterdam, Netherlands) · 2025
    Article
  7. Aqueous Extracts and Flavonoids Obtained fromPharmaceuticals (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Chaya Leaf: A Promising Approach for Diabetes Management.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  12. Review
  13. Metabolomic Profiling ofMolecules (Basel, Switzerland) · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xinrui YiCollege of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Mosi DongCollege of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Naifei GuoCollege of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Jinlong TianFood Science College, Shenyang Agricultural University, Shenyang, China.
Ping LeiCollege of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Song WangLiaoning Shengqi Haotian Biomedical Technology Co., Ltd., Liaoning, Shenyang, China.
Yufeng YangCollege of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Yan ShiCollege of Traditional Chinese Medicine, Liaoning University of Traditional Chinese Medicine, Shenyang, China.
Liaoning University of Traditional Chinese Medicine · CNShenyang Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of type 2 diabetes mellitus (T2DM) is increasing every year. Medications are currently the most common therapy for T2DM. However, these medications have certain adverse effects. In order to find safe and effective ways to improve this disease, researchers have discovered that some natural products can decrease blood sugar. Flavonoids are one of the most essential low molecular weight phenolic chemicals in the plant world, which widely exist in plant roots, stems, leaves, flowers, and fruits. They possess a variety of biological activities, including organ protection, hypoglycemic, lipid-lowering, anti-oxidative and anti-inflammatory effects. Some natural flavonoids ameliorate T2DM and its complications through anti-oxidation, anti-inflammatory action, glucose and lipid metabolism regulation, insulin resistance management, etc. Hence, this review aims at demonstrating the potential benefits of flavonoids in T2DM and its complications. This laid the foundation for the development of novel hypoglycemic medications from flavonoids.

Indexed as

FlavonoidsInflammatoryinsulin resistanceoxidative stressT2DM

Identifiers

PMID37324738
PMCPMC10265523
OpenAlexW4378903635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.