Evidence map›Paper›PMID 37324383›Full record

ArticleFrontiers in physiology2023

Comparing two extracellular additives to facilitate extended storage of red blood cells in a supercooled state.

Nishaka William, Ziya Isiksacan, Olga Mykhailova, Carly Olafson, Martin L Yarmush, O Berk Usta, Jason P Acker

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Thermodynamic Principles of Emerging Cryopreservation Technologies.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nishaka WilliamDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
Ziya IsiksacanCenter for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Olga MykhailovaInnovation and Portfolio Management, Canadian Blood Services, Edmonton, AB, Canada.
Carly OlafsonInnovation and Portfolio Management, Canadian Blood Services, Edmonton, AB, Canada.
Martin L YarmushCenter for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
O Berk UstaCenter for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Jason P AckerDepartment of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada.
Canadian Blood Services · CAHarvard University · USUniversity of Alberta · CARutgers, The State University of New Jersey · US

Funding

Deep Supercooling of Red Blood Cells: Towards Practical Long Term StorageR01HL145031 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI USTA, OSMAN BERK, YARMUSH, MARTIN L · 2020 to 2023
$1.5M
Deep Supercooling of Liver Cells and 2D and 3D Tissue Constructs: Effect of AttachmentR21GM136002 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI USTA, OSMAN BERK · 2019 to 2020
$462k
NHLBI NIH HHS R01 HL145031NIGMS NIH HHS R21 GM136002
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

nucleationpolyethylene glycolred blood cellsstorage lesionsupercoolingsurface-sealingtrehalose

Identifiers

PMID37324383
PMCPMC10267403
OpenAlexW4379055675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.