Evidence map›Paper›PMID 37324352›Full record

ArticleJTCVS techniques2023

Use of aortic wall patches as leaflet replacement material during aortic valve repair.

John L Myers, J Brian Clark, Timothy W James, Emily Downs, Saad M Hasan, Robert S Binford, Jeffrey D McNeil, Victor M Rodriquez, Christopher E Mascio, Lawrence M Wei and 2 more

Abstract read
In one paragraph

Article in JTCVS techniques, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

John L MyersPennsylvania State University, Hershey, Pa.
J Brian ClarkPennsylvania State University, Hershey, Pa.
Timothy W JamesSt Joseph's Hospital, Tacoma, Wash.
Emily DownsUniversity of Virginia, Charlottesville, Va.
Saad M HasanChrist Hospital, Cincinnati, Ohio.
Robert S BinfordOverlake Hospital, Bellevue, Wash.
Jeffrey D McNeilCardiothoracic and Vascular Surgeons of Austin, Austin, Tex.
Victor M RodriquezSutter Medical Center, Sacramento, Calif.
Christopher E MascioWest Virginia University, Morgantown, WVa.
Lawrence M WeiWest Virginia University, Morgantown, WVa.
Vinay BadhwarWest Virginia University, Morgantown, WVa.
J Scott RankinWest Virginia University, Morgantown, WVa.

Funding

Network for Cardiothoracic Surgical Investigations in Cardiovascular MedicineUM1HL088925 · NHLBI · UNIVERSITY OF VIRGINIA · PI BADHWAR, VINAY, KRON, IRVING L. · 2013 to 2025
$6.8M
NHLBI NIH HHS UM1 HL088925
6 · The paper itself

Abstract

Objectives: Aortic valve repair can be limited by inadequate leaflet tissue for proper coaptation. Various kinds of pericardium have been used for cusp augmentation, but most have failed because of tissue degeneration. A more durable leaflet substitute is needed. Methods: In this report, 8 consecutive cases are presented in which autologous ascending aortic tissue was used to augment inadequate native cusps during aortic valve repair. Biologically, aortic wall is a living autologous tissue that could have exceptional durability as a leaflet substitute. Techniques for insertion are described in detail, along with procedural videos. Results: Early surgical outcomes were excellent, with no operative mortalities or complications, and all valves were competent with low valve gradients. Patient follow-up and echocardiograms to a maximum of 8 months' postrepair remain excellent. Conclusions: Because of superior biologic characteristics, aortic wall has the potential to provide a better leaflet substitute during aortic valve repair and to expand patient categories amenable to autologous reconstruction. More experience and follow-up should be generated.

Indexed as

aortic leaflet replacementaortic valve repairleaflet defects

Identifiers

PMID37324352
PMCPMC10268232

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.