Evidence map›Paper›PMID 37324034›Full record

ReviewExploration (Beijing, China)2023

Revolving ATPase motors as asymmetrical hexamers in translocating lengthy dsDNA via conformational changes and electrostatic interactions in phi29, T7, herpesvirus, mimivirus,

Tao Weitao, Giovanna Grandinetti, Peixuan Guo

Open access · goldAbstract readReview
In one paragraph

Review in Exploration (Beijing, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Fusion of shallow and deep features fromQuantitative imaging in medicine and surgery · 2024
    Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tao WeitaoUT Southwestern Medical Center Center for the Genetics of Host Defense Dallas TX USA.
Giovanna GrandinettiCenter for Electron Microscopy and Analysis The Ohio State University Columbus OH USA.
Peixuan GuoCenter for RNA Nanobiotechnology and Nanomedicine Division of Pharmaceutics and Pharmacology, College of Pharmacy Dorothy M. Davis Heart and Lung Research Institute, James Comprehensive Cancer Center, College of Medicine The Ohio State University Columbus OH USA.ORCID https://orcid.org/0000-0001-5706-2833
The Ohio State University · USSouthwestern Medical Center · US

Funding

Phi29 Motor Nanopore for Single Molecule Sensing and dsDNA FingerprintingR01EB012135 · NIBIB · UNIVERSITY OF KENTUCKY · PI GUO, PEIXUAN · 2011 to 2019
$2.6M
Dissect the molecular mechanism of a viral genome packaging motor by an integrated structural approachR01GM141394 · NIGMS · OHIO STATE UNIVERSITY · PI CHENG, XIAOLIN, GUO, PEIXUAN · 2021 to 2024
$2.0M
NIBIB NIH HHS R01 EB012135NIGMS NIH HHS R01 GM141394
6 · The paper itself

Abstract

Investigations of the parallel architectures of biomotors in both prokaryotic and eukaryotic systems suggest a similar revolving mechanism in the use of ATP to drive translocation of the lengthy double-stranded (ds)DNA genomes. This mechanism is exemplified by the dsDNA packaging motor of bacteriophage phi29 that operates through revolving but not rotating dsDNA to "Push through a one-way valve". This unique and novel revolving mechanism discovered in phi29 DNA packaging motor was recently reported in other systems including the dsDNA packaging motor of herpesvirus, the dsDNA ejecting motor of bacteriophage T7, the plasmid conjugation machine TraB in

Indexed as

ATPasebacteriophage phi29DNA packagingDNA translocasehexamerViral DNA packaging motor

Identifiers

PMID37324034
PMCPMC10191066
OpenAlexW4319321700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.