Evidence map›Paper›PMID 37323941›Full record

ArticleAccess microbiology2023

Viral infectivity in paediatric SARS-CoV-2 clinical samples does not vary by age.

Madaline M Schmidt, Hannah W Despres, David J Shirley, Michael E Bose, Kate C McCaul, Jessica W Crothers, Kelly J Henrickson, Benjamin Lee, Emily A Bruce

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Access microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Madaline M SchmidtDepartment of Microbiology and Molecular Genetics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA.ORCID https://orcid.org/0000-0003-3893-3466
Hannah W DespresDepartment of Microbiology and Molecular Genetics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA.ORCID https://orcid.org/0000-0003-0321-5202
David J ShirleyData Science Department, Faraday, Inc., Burlington, VT, USA.ORCID https://orcid.org/0000-0003-4529-0403
Michael E BoseDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Kate C McCaulDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Jessica W CrothersDepartment of Pathology and Laboratory Medicine, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA.
Kelly J HenricksonDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Benjamin LeeDepartment of Pediatrics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA.
Emily A BruceDepartment of Microbiology and Molecular Genetics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA.ORCID https://orcid.org/0000-0001-8391-370X
University of Vermont · USMedical College of Wisconsin · USFaraday Technology (United States) · US

Funding

Vermont Immunology/Infectious Diseases CenterP30GM118228 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BUDD, RALPH C · 2016 to 2021
$6.8M
NIGMS NIH HHS P30 GM118228
6 · The paper itself

Abstract

At the start of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there was much uncertainty about the role of children in infection and transmission dynamics. Through the course of the pandemic, it became clear that children were susceptible to SARS-CoV-2 infection, although they were experiencing a notable lack of severe disease outcomes as compared to the adult population. This trend held true with the emergence of new SARS-CoV-2 variants, even in paediatric populations that were ineligible to be vaccinated. The difference in disease outcomes has prompted questions about the virological features of SARS-CoV-2 infection in this population. In order to determine if there was any difference in the infectivity of the virus produced by children with coronavirus disease 2019 (COVID-19), we compared viral RNA levels (clinical RT-qPCR

Indexed as

clinical isolatespaediatricSARS-CoV-2viral infectivity

Identifiers

PMID37323941
PMCPMC10267661
OpenAlexW4378472552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.