Evidence map›Paper›PMID 37323819›Full record

ArticleOncology letters2023

Primary hepatic neuroendocrine neoplasm presenting as a massive cystic liver tumor mimicking mucinous cystic neoplasm of the liver: A case report and literature review.

Takuji Noro, Teppei Tatsuoka, Musashi Takada, Souya Meguro, Hirotaka Ishido, Keishi Kawasaki, Takashi Mitsui, Emiko Takeshita, Taiki Sato, Sinichi Ban and 3 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Oncology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Primary Hepatic Neuroendocrine Neoplasms: Systematic Review and Expert Pathologist Reappraisal Using the WHO 6th Edition Framework.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Takuji NoroDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Teppei TatsuokaDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Musashi TakadaDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Souya MeguroDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Hirotaka IshidoDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Keishi KawasakiDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Takashi MitsuiDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Emiko TakeshitaDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Taiki SatoDepartment of Pathology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Sinichi BanDepartment of Pathology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Hidehiro TajimaDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Takashi OkuyamaDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Hideyuki YoshitomiDepartment of Surgery, Dokkyo Medical University Saitama Medical Center, Koshigaya, Saitama, 343-8555, Japan.
Social Insurance Saitama Chuo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendocrine neoplasms (NENs) preferentially arise in the bronchopulmonary tree or the gastrointestinal tract. Notably, primary hepatic NENs are extremely rare. The present study describes a case of hepatic NEN presenting as a giant hepatic cystic lesion. A 42-year-old woman presented with a large liver tumor. Contrast-enhanced abdominal computed tomography revealed a cystic tumor (18 cm) in their left liver. The tumor exhibited liquid components and mural solid nodules with enhanced effects. The lesion was diagnosed as mucinous cystic carcinoma (MCC) preoperatively. The patient underwent a left hepatectomy, and the postoperative course was uneventful. The patient has been alive without recurrence for 36 months postoperatively. The pathological diagnosis was NEN G2. This patient had ectopic pancreatic tissue in the liver and thus the ectopic pancreatic origin of the tumor was suspected. The present study describes a case of resected cystic primary NEN of the liver that was difficult to differentiate from mucinous cystic neoplasms. As primary liver NENs are extremely rare, further studies are needed to establish their diagnosis and treatment.

Indexed as

cystic tumor of the liverectopic pancreashuge liver tumormucinous cystic neoplasmsprimary hepatic neuroendocrine neoplasms

Identifiers

PMID37323819
PMCPMC10265362
OpenAlexW4378906458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.