ArticleExploration (Beijing, China)2021
3D-printed microneedles with open groove channels for liquid extraction.
Article in Exploration (Beijing, China), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The trial behind it
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Who cites it
20 citing papers in PubMed.
- Chimeric antigen receptor (CAR)-T cell therapy for solid tumors in pediatric patients: current breakthroughs, dilemmas, and strategies.Experimental hematology & oncology · 2026Review
- A Portable and Dual-Button Microneedle Device Enables Intelligent Multimodal Laser Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Barrier-disrupting microneedle technology: Overcoming physical, physiological, and pathological skin defenses to enhance therapeutic efficacy.Bioactive materials · 2026Review
- Machine Learning-Driven Multi-Objective Optimization of Bead Geometry and Energy Efficiency in Laser-Arc Hybrid Additive Manufacturing.Materials (Basel, Switzerland) · 2025Article
- Sustainable MXene/Conductive Cellulose Heteroinks for 3D Printed High Areal Energy Density Micro-Supercapacitors and Self-Powered Integrated Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Advances in the development of microarray patches in biomedicine.New biotechnology · 2025Review
- Fabrication of 3D Printed Microneedle Patch for the Simultaneous Delivery and Detection of Melatonin from Interstitial Fluid.AAPS PharmSciTech · 2025Article
- A Spatially Distributed Microneedle System for Bioorthogonal T Cell-Guided Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A Smart Semi-Implantable Device Integrating Microchannel-Enhanced Sampling and Multiplex Biochemical Testing for Deep Wound Monitoring and Pathogen Identification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Microneedle Technology for Overcoming Biological Barriers: Advancing Biomacromolecular Delivery and Therapeutic Applications in Major Diseases.Research (Washington, D.C.) · 2025Review
- Advances in Microneedle Drug Delivery for Obesity: Mechanisms, Applications, and Perspectives.International journal of nanomedicine · 2025Review
- Wearable and battery-free wound dressing system for wireless and early sepsis diagnosis.Bioengineering & translational medicine · 2023Article
- Image Processing Approach to Investigate the Correlation between Machining Parameters and Burr Formation in Micro-Milling Processes of Selective-Laser-Melted AISI 316L.Micromachines · 2023Article
- 3D bio-printed living nerve-like fibers refine the ecological niche for long-distance spinal cord injury regeneration.Bioactive materials · 2023Article
- Tissue adhesive hemostatic microneedle arrays for rapid hemorrhage treatment.Bioactive materials · 2023Article
- Microneedles forMaterials today. Bio · 2023Review
- A Review of 3D-Printing of Microneedles.Pharmaceutics · 2022Review
- The marriage of Xenes and hydrogels: Fundamentals, applications, and outlook.Innovation (Cambridge (Mass.)) · 2022Review
- 3D-Printed Microneedles for Point-of-Care Biosensing Applications.Micromachines · 2022Article
- 3D-printed microneedles with open groove channels for liquid extraction.Exploration (Beijing, China) · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microneedles (MNs) offer a simple and minimally invasive way to sample skin interstitial fluid for bioanalysis. Through the integration with portable or wearable sensing devices, it allows us to get qualitative information about some biomarkers in situ. This work is to show a MN platform with open groove channels that are manufactured using photopolymerization 3D printing. The grooves on the needle surface permit that liquid flows from the tips to the base under the influence of capillary force. The ultimate MN device can penetrate skin and tissues and sample liquid in the skin model. By taking the glucose as the model biomarker, we demonstrate that the biomarkers in the extracted liquid can be analyzed in situ by the commercial test strips attached to the back.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.