Evidence map›Paper›PMID 37323691›Full record

ReviewExploration (Beijing, China)2021

Advanced microfluidic devices for fabricating multi-structural hydrogel microsphere.

Zehao Chen, Zhendong Lv, Zhen Zhang, David A Weitz, Hongbo Zhang, Yuhui Zhang, Wenguo Cui

Open access · goldAbstract readReview
In one paragraph

Review in Exploration (Beijing, China), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 115 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. [Preparation of B@PH/GM-V hydrogel microspheres and their antioxidant and osteogenesis-promoting effects].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Hydrogel-Based Continuum Soft Robots.Gels (Basel, Switzerland) · 2025
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Zehao ChenSchool of Mechatronic Engineering and Automation Shanghai University Shanghai P. R. China.
Zhendong LvDepartment of Spine Surgery Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai P. R. China.
Zhen ZhangSchool of Mechatronic Engineering and Automation Shanghai University Shanghai P. R. China.
David A WeitzDepartment of Physics and Harvard John A. Paulson School of Engineering and Applied Sciences Harvard University Cambridge Massachusetts USA.
Hongbo ZhangPharmaceutical Sciences Laboratory Åbo Akademi University and Turku Bioscience Centre University of Turku and Åbo Akademi University Turku Finland.
Yuhui ZhangSchool of Mechatronic Engineering and Automation Shanghai University Shanghai P. R. China.
Wenguo CuiDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai P. R. China.ORCID https://orcid.org/0000-0002-6938-9582
Shanghai University · CNShanghai Jiao Tong University · CNÅbo Akademi University · FIHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogel microspheres are a novel functional material, arousing much attention in various fields. Microfluidics, a technology that controls and manipulates fluids at the micron scale, has emerged as a promising method for fabricating hydrogel microspheres due to its ability to generate uniform microspheres with controlled geometry. With the development of microfluidic devices, more complicated hydrogel microspheres with multiple structures can be constructed. This review presents an overview of advances in microfluidics for designing and engineering hydrogel microspheres. It starts with an introduction to the features of hydrogel microspheres and microfluidic techniques, followed by a discussion of material selection for fabricating microfluidic devices. Then the progress of microfluidic devices for single-component and composite hydrogel microspheres is described, and the method for optimizing microfluidic devices is also given. Finally, this review discusses the key research directions and applications of microfluidics for hydrogel microsphere in the future.

Indexed as

biomaterialshydrogel microspheresmicrofluidic devicesmicrofluidics

Identifiers

PMID37323691
PMCPMC10191056
OpenAlexW4200355601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.