Evidence map›Paper›PMID 37323422›Full record

ArticleOpen forum infectious diseases2023

Bacteremia During the First Year After Solid Organ Transplantation: An Epidemiological Update.

Dionysios Neofytos, Susanne Stampf, Linard D Hoessly, Matilde D'Asaro, Gael Nguyen Tang, Katia Boggian, Cedric Hirzel, Nina Khanna, Oriol Manuel, Nicolas J Mueller and 2 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Observational
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Burden and Management of Multi-Drug Resistant Organism Infections in Solid Organ Transplant Recipients Across the World: A Narrative Review.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  15. Observational
  16. Early Onset Bacteremia in Kidney Transplant Recipients in the Current Era.Transplant infectious disease : an official journal of the Transplantation Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Dionysios NeofytosTransplant Infectious Diseases Unit, Division of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-6970-2869
Susanne StampfClinic for Transplantation Immunology and Nephrology (Swiss Transplant Cohort Study), University Hospital of Basel, Basel, Switzerland.
Linard D HoesslyClinic for Transplantation Immunology and Nephrology (Swiss Transplant Cohort Study), University Hospital of Basel, Basel, Switzerland.
Matilde D'AsaroTransplant Infectious Diseases Unit, Division of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Gael Nguyen TangTransplant Infectious Diseases Unit, Division of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Katia BoggianDivision of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland.
Cedric HirzelDepartment of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Nina KhannaDivision of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0002-2642-419X
Oriol ManuelDivision of Infectious Diseases, University Hospital of Vaud, Lausanne, Switzerland.
Nicolas J MuellerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, Switzerland.
Christian Van DeldenTransplant Infectious Diseases Unit, Division of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
Swiss Transplant Cohort Study
Hôpital Beau-Séjour · CHUniversity Hospital of Basel · CHUniversity Hospital of Geneva · CHUniversity of Lausanne · CHUniversity Hospital of Zurich · CHUniversity of Bern · CHUniversity of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There are limited contemporary data on the epidemiology and outcomes of bacteremia in solid organ transplant recipients (SOTr). Methods: Using the Swiss Transplant Cohort Study registry from 2008 to 2019, we performed a retrospective nested multicenter cohort study to describe the epidemiology of bacteremia in SOTr during the first year post-transplant. Results: Of 4383 patients, 415 (9.5%) with 557 cases of bacteremia due to 627 pathogens were identified. One-year incidence was 9.5%, 12.8%, 11.4%, 9.8%, 8.3%, and 5.9% for all, heart, liver, lung, kidney, and kidney-pancreas SOTr, respectively ( Conclusions: Almost 1/10 SOTr may develop bacteremia during the first year post-transplant associated with low mortality. Lower bacteremia rates have been observed since 2014 and in patients receiving cotrimoxazole prophylaxis. Variabilities in incidence, timing, and pathogen of bacteremia across different SOT types may be used to tailor prophylactic and clinical approaches.

Indexed as

bacteremiabloodstream infectionclinical outcomesepidemiologyrisk factorssolid organ transplanttiming

Identifiers

PMID37323422
PMCPMC10267299
OpenAlexW4372256711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.