Evidence map›Paper›PMID 37323400›Full record

ArticleACS omega2023

Kingshuk Bag, Aditya Kumar Pal, Subhadip Basu, Mamta Singla, Biplab Sarkar, Dipankar Chatterji, Prabal Kumar Maiti, Anirban Ghosh, Narayanaswamy Jayaraman

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kingshuk BagDepartment of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India.
Aditya Kumar PalMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.ORCID https://orcid.org/0000-0003-3005-7668
Subhadip BasuDepartment of Physics, Indian Institute of Science, Bangalore 560 012, India.
Mamta SinglaMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Biplab SarkarMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Dipankar ChatterjiMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.ORCID https://orcid.org/0000-0002-9985-0632
Prabal Kumar MaitiDepartment of Physics, Indian Institute of Science, Bangalore 560 012, India.ORCID https://orcid.org/0000-0002-9956-1136
Anirban GhoshMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Narayanaswamy JayaramanDepartment of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India.ORCID https://orcid.org/0000-0001-5577-8053
Indian Institute of Science Bangalore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperphosphorylated nucleotide (p)ppGpp, synthesized by Rel protein, regulates the stringent response pathway responsible for biofilm and persister cell growth in mycobacteria. The discovery of vitamin C as an inhibitor of Rel protein activities raises the prospect of tetrone lactones to prevent such pathways. The closely related isotetrone lactone derivatives are identified herein as inhibitors of the above processes in a mycobacterium. Synthesis and biochemical evaluations show that an isotetrone possessing phenyl substituent at

Identifiers

PMID37323400
PMCPMC10268289
OpenAlexW4378903728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.