Evidence map›Paper›PMID 37323010›Full record

Observational studyArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2024

A Closer Look at Practice Effects in Mild Cognitive Impairment and Alzheimer's Disease.

Kevin Duff, Ava Dixon, Lindsay Embree

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Addressing Practice Effects in Population-Based Studies of Trends in Late-Life Dementia and Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kevin DuffLayton Aging and Alzheimer's Disease Center, Department of Neurology, Oregon Health & Science University, Portland, OR, USA.ORCID 0000-0002-9336-2400
Ava DixonCenter for Alzheimer's Care, Imaging and Research, Department of Neurology, University of Utah, Salt Lake City UT, USA.
Lindsay EmbreeCenter for Alzheimer's Care, Imaging and Research, Department of Neurology, University of Utah, Salt Lake City UT, USA.
University of Utah · USOregon Health & Science University · US

Funding

Research Education ComponentP30AG066518 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Zachary Beattie · 2020 to 2026
$28.6M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
University of Utah Center for Clinical and Translational Science-UL1UL1TR000105 · NCATS · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2012 to 2013
$5.1M
Enriching clinical trials requiring amyloid positivity with practice effectsR01AG055428 · NIA · UNIVERSITY OF UTAH · PI DUFF, KEVIN M, HOFFMAN, JOHN M · 2017 to 2021
$3.6M
NCRR NIH HHS UL1 RR025764NIA NIH HHS P30 AG066518NIA NIH HHS R01AG055428NIH HHS 8UL1TR000105
6 · The paper itself

Abstract

Practice effects have become a potentially important variable regarding the diagnosis, prognosis, and treatment recommendations in mild cognitive impairment (MCI) and Alzheimer's disease (AD). However, the understanding of these short-term changes in test scores remains unclear. The current observational study sought to examine variables that influence the magnitude of short-term practice effects in MCI and AD, including demographic information, cognitive performance, daily functioning, and medical comorbidities. One hundred sixty-six older adults classified as cognitively intact, amnestic MCI, or mild AD were tested twice across 1 week with a brief battery of neuropsychological tests. Correlational and regression analyses examined the relationship of practice effects with demographic and clinical variables. Results indicated that practice effects were minimally related to demographic variables and medical comorbidities, but they were significantly related to cognitive variables, depressive symptoms, and daily functioning. These findings expand our understanding of practice effects in MCI and AD, and they may allow a better appreciation of how they could affect clinical care and research.

Indexed as

Alzheimer DiseaseCognitive DysfunctionAgedHumansNeuropsychological TestsPrognosisAlzheimer’s diseaseMild cognitive impairmentPractice effects

Identifiers

PMID37323010
PMCPMC10802223
OpenAlexW4380854587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.