ArticleBMC public health2023
Feasibility and acceptability of peer-delivered HIV self-testing and PrEP for young women in Kampala, Uganda.
Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Implementation components and delivery structures of adolescent peer navigation as a workforce model: a scoping review.BMC global and public health · 2026Pooled it
- A systematic review of the effectiveness of participatory, health system-based interventions to improve the sexual and reproductive health and rights of adolescent girls and young women in Sub-Saharan Africa.Sexual and reproductive health matters · 2025Pooled it
- Acceptability and use of HIV self-testing among young people in sub-Saharan Africa: a mixed methods systematic review.BMC primary care · 2024Pooled it
- Effect of a Peer Support Intervention for Oral Pre-Exposure Prophylaxis Uptake and Adherence Among Adolescent Girls and Young Women at Risk of HIV Acquisition in Kampala, Uganda: A Randomized Controlled Trial.Journal of the International AIDS Society · 2026Trial
- Findings From the Todurujo na Kadurok (Empowering Youth) HIV Self-Testing and Edutainment Comic Randomized Controlled Trial With Refugee Youth in a Humanitarian Setting in Uganda.Journal of the International Association of Providers of AIDS CareTrial
- Determinants of PrEP Delivery Platform Choice in Adolescents and Young People: The Fast-PrEP Project in Cape Town, South Africa.International journal of environmental research and public health · 2026Article
- Exploring Adolescent Girls' and Young Women's Perceptions of HIV Prevention Pre-exposure Prophylaxis Use: A Qualitative Synthesis of Evidence from Sub-Saharan Africa.AIDS and behavior · 2026Review
- Review
- Oral PrEP use among pregnant or parenting young women in South Africa: evidence from a large community-based implementation study.BMC public health · 2026Article
- Perceived barriers and facilitators to the feasibility and acceptability of a peer-to-peer (P2P) HIV self-testing distribution model among adolescents and young people aged 15-24 years in Uganda: a qualitative study.BMJ public health · 2026Article
- Acceptability, appropriateness, willingness to use, and perceptions towards HIV self-testing among adolescent girls and young women in rural Northern Uganda: a baseline formative cross-sectional study.Implementation science communications · 2025Article
- Stakeholder Perspectives on a Community-Based Peer-Led Biomedical HIV Prevention Intervention for Women Who Engage in Sex Work in Southwestern Uganda: Results from a Qualitative Study.AIDS and behavior · 2025Article
- Feasibility, acceptability and preliminary effects of a social network-based, peer-led HIV self-testing intervention among men in two Ugandan fishing communities, 2022.Archives of public health = Archives belges de sante publique · 2025Article
- A qualitative study of peer education experiences and oral pre-exposure prophylaxis use among adolescent girls and young women at high risk of HIV acquisition in Kampala, Uganda.Frontiers in public health · 2025Article
- Women's preferences for integrating multi-product pre-exposure prophylaxis delivery programs within services for sexually transmitted infections and reproductive health care in Uganda: a discrete choice experiment.Frontiers in reproductive health · 2025Article
- Adolescent girls and young women as a critical population for HIV epidemic control in sub-Saharan Africa: are we doing enough?Frontiers in public health · 2025Article
- Stakeholder considerations on acceptability and implementation of a novel rapid test for acute HIV infection: A qualitative study in Indiana.PLOS global public health · 2025Article
- Perceptions, acceptability, and utilization of HIV self-testing kits among young people in urban slums in Kampala.Frontiers in public health · 2025Article
- Feasibility, acceptability and preliminary effect of a community-led HIV self-testing model among adolescent girls and young women in Rural Northern Uganda: a quasi-experimental study protocol.Implementation science communications · 2024Article
- Stakeholder-engaged development of a rapid test for detection of acute HIV infection.Research square · 2024Article
Corrections and comments
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Authors and funding
25 authors.
Funding
Abstract
backgroundAdolescent girls and young women (AGYW) account for 29% of new HIV infections in Uganda despite representing just 10% of the population. Peer support improves AGYW linkage to HIV care and medication adherence. We evaluated the feasibility and acceptability of peer delivered HIV self-tests (HIVST) and oral pre-exposure prophylaxis (PrEP) to young women in Uganda.
methodsBetween March and September 2021, we conducted a pilot study of 30 randomly selected young women, aged 18-24 years, who had received oral PrEP for at least three months, but had suboptimal adherence as measured by urine tenofovir testing (< 1500 ng/ml). Participants were offered daily oral PrEP and attended clinic visits three and six months after enrollment. Between clinic visits, participants were visited monthly by trained peers who delivered HIVST and PrEP. Feasibility and acceptability of peer-delivered PrEP and HIVST (intervention) were measured by comparing actual versus planned intervention delivery and product use. We conducted two focus groups with young women, and five in-depth interviews with peers and health workers to explore their experiences with intervention delivery. Qualitative data were analyzed using thematic analysis.
resultsAt baseline, all 30 enrolled young women (median age 20 years) accepted peer-delivered PrEP and HIVST. Peer delivery visit completion was 97% (29/30) and 93% (28/30) at three and six months, respectively. The proportion of participants with detectable tenofovir in urine was 93% (27/29) and 57% (16/28) at months three and six, respectively. Four broad themes emerged from the qualitative data: (1) Positive experiences of peer delivered HIVST and PrEP; (2) The motivating effect of peer support; (3) Perceptions of female controlled HIVST and PrEP; and (4) Multi-level barriers to HIVST and PrEP use. Overall, peer delivery motivated young women to use HIVST and PrEP and encouraged persistence on PrEP by providing non-judgmental client-friendly services and adherence support.
conclusionPeer delivery of HIVST and oral PrEP was feasible and acceptable to this sample of young women with suboptimal PrEP adherence in Uganda. Future larger controlled studies should evaluate its effectiveness among African AGWY.
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