ArticleBMC microbiology2023
Prematurely delivering mothers show reductions of lachnospiraceae in their gut microbiomes.
Article in BMC microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Longitudinal dynamics of the maternal gut virome associate with metabolic features of preterm birth.Nature communications · 2026Article
- Maternal anemia during pregnancy and its association with the gut microbiota profile in pregnant and postpartum women, and their infants: a cohort study.The American journal of clinical nutrition · 2025Article
- Butyrate-producing bacteria in pregnancy maintenance: mitigating dysbiosis-induced preterm birth.Journal of translational medicine · 2025Article
- Dynamic changes in the pregnancy microbiome and their role in preterm birth.Frontiers in cellular and infection microbiology · 2025Review
- Correlation Analyses of the Consumption of Artificial Sweeteners During Pregnancy and the Incidence of Gestational Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Effects of Spent Substrate of Oyster Mushroom (Animals : an open access journal from MDPI · 2024Article
- Amniotic fluid proteomic analysis identifies IL1RL1, APOE, and NECTIN4 as new biomarkers for preterm birth.BMC pregnancy and childbirth · 2024Article
- The maternal gut microbiome in pregnancy: implications for the developing immune system.Nature reviews. Gastroenterology & hepatology · 2024Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm birth is the leading cause of perinatal morbidity and mortality. Despite evidence shows that imbalances in the maternal microbiome associates to the risk of preterm birth, the mechanisms underlying the association between a perturbed microbiota and preterm birth remain poorly understood.
methodApplying shotgun metagenomic analysis on 80 gut microbiotas of 43 mothers, we analyzed the taxonomic composition and metabolic function in gut microbial communities between preterm and term mothers.
resultsGut microbiome of mothers delivering prematurely showed decreased alpha diversity and underwent significant reorganization, especially during pregnancy. SFCA-producing microbiomes, particularly species of Lachnospiraceae, Ruminococcaceae, and Eubacteriaceae, were significantly depleted in preterm mothers. Lachnospiraceae and its species were the main bacteria contributing to species' differences and metabolic pathways.
conclusionGut microbiome of mothers delivering prematurely has altered and demonstrates the reduction of Lachnospiraceae.
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Registered trials
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