Evidence map›Paper›PMID 37322230›Full record

ArticleImmunogenetics2023

Complement component C1q is an immunological rheostat that regulates Fc:Fc

Edward C So, Hua Zhou, Ariana Greenwell, Erin E Burch, Yaping Ji, Emmanuel Y Mérigeon, Henrik S Olsen, Søren M Bentzen, David S Block, Xiaoyu Zhang and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Decoding Local Adaptation in the Exploited Native Marine MusselInternational journal of molecular sciences · 2025
    Article
  2. C1QA is an invariant biomarker for tissue macrophages.bioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Serum immunoglobulin and the threshold of Fc receptor-mediated immune activation.Biochimica et biophysica acta. General subjects · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Edward C SoDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Hua ZhouDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Ariana GreenwellDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Erin E BurchDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Yaping JiDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Emmanuel Y MérigeonGliknik Inc., Baltimore, MD, USA.
Henrik S OlsenGliknik Inc., Baltimore, MD, USA.
Søren M BentzenDepartment of Epidemiology and Public Health, Division of Biostatistics and Bioinformatics, University of Maryland School of Medicine, Baltimore, MD, USA.
David S BlockGliknik Inc., Baltimore, MD, USA.
Xiaoyu Zhang *Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Scott E Strome *Department of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center (UTHSC), 910 Madison Avenue, 10th floor Suite 1002, Memphis, TN, 38163, USA. sstrome@uthsc.edu.
University of Maryland, Baltimore · USGliknik (United States) · USUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though binding sites for the complement factor C1q and the canonical fragment crystallizable (Fc) gamma receptors (Fc

Indexed as

Complement C1qReceptors, IgGAntibody-Dependent Cell CytotoxicityHumansImmunoglobulin GKiller Cells, NaturalComplement C1qImmunoglobulin GReceptors, IgGAntibodyC1qComplementFc receptoprIgGImmune complex

Identifiers

PMID37322230
OpenAlexW4380715020

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.