ArticleClinical and experimental pediatrics2024
Skin and oral intervention for food allergy prevention based on dual allergen exposure hypothesis.
Article in Clinical and experimental pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Effect of Dupilumab on Allergen-Specific IgE Levels and Clinical Tolerance in Patients with Food Allergy: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- TRANS-FOODS study protocol: an observer-blinded, randomized controlled study to assess transcutaneous sensitization to peanut protein in adults with and without atopic dermatitis.Skin health and disease · 2026Article
- Early-Life Biomarkers in Food Allergy Development: A Systematic Review of Immunological and Intestinal Pathways.Biomedicines · 2026Review
- Early Walnut Powder Introduction for Prevention of Walnut Sensitisation in High-Risk Infants With Eczema: An Open-Label, Randomised, Non-Inferiority Trial.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Article
- Environmental food allergen levels in the homes of 3-4-month-old infants: findings from the second phase Chiba study of mother and child health (2nd C-MACH).Scientific reports · 2026Article
- Diversity of complementary diet and early food allergy risk.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- Maternal influences on offspring food allergy.Immunological reviews · 2024Review
- Feasibility and Safety of the Early Introduction of Allergenic Foods in Asian Infants with Eczema.Nutrients · 2024Article
- Predictive modeling for cow's milk allergy remission by low-dose oral immunotherapy in young children.The World Allergy Organization journal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Early-onset atopic dermatitis increases an individual's risk of food allergies, suggesting that transcutaneous sensitization may occur through inflamed skin. Regarding food allergy causation, the dual allergen exposure hypothesis proposes that oral allergen exposure leads to immune tolerance, whereas allergen exposure via inflamed skin causes food allergies. This hypothesis suggests that it is important to induce oral immune tolerance and prevent allergic food sensitization through the skin. This review focuses on the breakthrough evidence based on the dual allergen exposure hypothesis that involves both skin and oral interventions for food allergy prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.