Evidence map›Paper›PMID 37319139›Full record

ArticlePLoS neglected tropical diseases2023

A global call for action to tackle skin-related neglected tropical diseases (skin NTDs) through integration: An ambitious step change.

Rie R Yotsu, L Claire Fuller, Michele E Murdoch, Wim H van Brakel, Chandrakant Revankar, Mahoutondji Yves Thierry Barogui, Jose Antonio Ruiz Postigo, Daniel Argaw Dagne, Kingsley Asiedu, Roderick J Hay

Registry-linked trialAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06918665 (HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06918665 phase1suspendednot on this mapstarted 2026, after this paper: background citation

HEALTH Trial - Healthy Adult Evaluation of Ivermectin Bioequivalence: Infant Versus Standard Formulation

TypeinterventionalSponsorMurdoch Childrens Research InstituteRan2026 to 2027Enrolled52ConditionsScabiesArmsivermectin infant formula preparation, Standard ivermectin 3mg tablet
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. The neglected majority: Inverse relationship between prevalence and global research activity of 15 dermatological diseases.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Independent assessment of the WHO Skin Neglected Tropical Diseases application for leprosy detection.Revista panamericana de salud publica = Pan American journal of public health · 2026
    Article
  12. Article
  13. Buruli ulcer.Nature reviews. Disease primers · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Buruli ulcer: Current landscape, challenges, and future directions.Journal of clinical tuberculosis and other mycobacterial diseases · 2025
    Article
  19. Review
  20. Buruli ulcer: An epidemiological update from Japan.The Journal of dermatology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rie R YotsuTulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, United States of America.ORCID 0000-0001-9102-1912
L Claire FullerInternational Foundation for Dermatology, London, United Kingdom.
Michele E MurdochDepartment of Dermatology, West Herts Teaching Hospitals NHS Trust, Watford General Hospital, Watford, United Kingdom.
Wim H van BrakelNLR International, Amsterdam, the Netherlands.
Chandrakant RevankarElimination of NTDs (Independent), North Brunswick, New Jersey, United States of America.
Mahoutondji Yves Thierry BaroguiWorld Health Organization, Regional Office for Africa, Libreville, Gabon.
Jose Antonio Ruiz PostigoWorld Health Organization Headquarters, Geneva, Switzerland.
Daniel Argaw DagneWorld Health Organization Headquarters, Geneva, Switzerland.
Kingsley AsieduWorld Health Organization Headquarters, Geneva, Switzerland.
Roderick J HayKing's College, London, United Kingdom.

Funding

World Health Organization 001
6 · The paper itself

Abstract

On 8 June 2022, the World Health Organization (WHO) released pivotal guidance, "Ending the neglect to attain the Sustainable Development Goals: A strategic framework for integrated control and management of skin-related neglected tropical diseases." Skin-related neglected tropical diseases, or skin NTDs, comprise a group of NTDs that produce signs and symptoms on the skin and include at least 9 diseases or disease groups. Moving away from disease-specific approaches, it is anticipated that synergies will be identified and integrated building on this shared feature, where possible, to achieve a greater health impact. This paper intends to draw attention to the prospects created by this scheme. The framework is a key basis for a proposal produced by WHO dedicated to skin NTD integration and describes the practical opportunities for this evolving strategy. It underlines the wider health benefits that will follow, thus working towards Universal Health Coverage and skin health for all.

Indexed as

Neglected DiseasesTropical MedicineGlobal HealthHumansSustainable DevelopmentWorld Health Organization

Identifiers

PMID37319139
PMCPMC10270348

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.