Evidence map›Paper›PMID 37319116›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Kathleen E Kyle, Sara P Puckett, Andrés Mauricio Caraballo-Rodríguez, José Rivera-Chávez, Robert M Samples, Cody E Earp, Huzefa A Raja, Cedric J Pearce, Madeleine Ernst, Justin J J van der Hooft and 5 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Novel peptaibiotics identified from Trichoderma clade Viride.Natural products and bioprospecting · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. ACS omega · 2023
    Article
  11. Resistance waxes for mutualists protected by wasp secretions.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 5 countries.

Kathleen E KyleDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269.ORCID 0000-0002-2837-1124
Sara P PuckettDivision of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269.ORCID 0000-0002-0211-3098
Andrés Mauricio Caraballo-RodríguezCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093-0657.ORCID 0000-0001-5499-2728
José Rivera-ChávezDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC 27402.ORCID 0000-0002-9225-6200
Robert M SamplesDivision of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269.
Cody E EarpDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC 27402.ORCID 0000-0003-2826-0480
Huzefa A RajaDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC 27402.ORCID 0000-0002-0824-9463
Cedric J PearceMycosynthetix, Inc., Hillsborough, NC 27278.ORCID 0000-0002-0212-1127
Madeleine ErnstDepartment of Congenital Disorders, Section for Clinical Mass Spectrometry, Danish Center for Neonatal Screening, Statens Serum Institut, 2300 Copenhagen, Denmark.ORCID 0000-0001-9530-3837
Justin J J van der HooftBioinformatics Group, Wageningen University & Research, 6708 PB Wageningen, the Netherlands.ORCID 0000-0002-9340-5511
Madison E AdamsDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269.ORCID 0000-0001-7961-5726
Nicholas H OberliesDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC 27402.ORCID 0000-0002-0354-8464
Pieter C DorresteinCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093-0657.
Jonathan L KlassenDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269.ORCID 0000-0003-1745-8838
Marcy J BalunasDivision of Medicinal Chemistry, Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269.ORCID 0000-0003-2374-4048
University of Connecticut · USUniversity of North Carolina at Greensboro · USUniversity of California San Diego · USMycosynthetix (United States) · USStatens Serum Institut · DKUniversity of Johannesburg · ZA

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI JIMMY ORJALA · 2007 to 2026
$27.2M
TrainingP41GM103484 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANDEIRA, NUNO · 2012 to 2018
$8.7M
Unified Computation Tools for Natural Products ResearchR01GM107550 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COTTRELL, GARRISON W, GERWICK, WILLIAM HENRY · 2013 to 2025
$8.2M
NCI NIH HHS P01 CA125066NIGMS NIH HHS P41 GM103484NIGMS NIH HHS R01 GM107550
6 · The paper itself

Abstract

Fungus-growing ants depend on a fungal mutualist that can fall prey to fungal pathogens. This mutualist is cultivated by these ants in structures called fungus gardens. Ants exhibit weeding behaviors that keep their fungus gardens healthy by physically removing compromised pieces. However, how ants detect diseases of their fungus gardens is unknown. Here, we applied the logic of Koch's postulates using environmental fungal community gene sequencing, fungal isolation, and laboratory infection experiments to establish that

Indexed as

AntsLaboratory InfectionTrichodermaAnimalsCuesGardensPeptaibolsSymbiosisPeptaibolscomparative metabolomicsfungus-growing antshost–microbe interactionspeptaibolsTrichoderma

Identifiers

PMID37319116
PMCPMC10288546
OpenAlexW4380852844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.