Evidence map›Paper›PMID 37318981›Full record

ArticleeLife2023

Bacterial meningitis in the early postnatal mouse studied at single-cell resolution.

Jie Wang, Amir Rattner, Jeremy Nathans

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Article
  9. Redefining CNS immune privilege.Nature reviews. Immunology · 2025
    Review
  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jie WangDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United States.
Amir RattnerDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United States.ORCID 0000-0001-9542-6212
Jeremy NathansDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United States.ORCID 0000-0001-8106-5460
Howard Hughes Medical Institute · USJohns Hopkins University · US

Funding

The control of retinal vascular development by Norrin and Frizzled4R01EY018637 · NEI · JOHNS HOPKINS UNIVERSITY · PI NATHANS, JEREMY · 2008 to 2021
$5.5M
NEI NIH HHS R01 EY018637NEI NIH HHS R01EY018637
6 · The paper itself

Abstract

Bacterial meningitis is a major cause of morbidity and mortality, especially among infants and the elderly. Here, we study mice to assess the response of each of the major meningeal cell types to early postnatal

Indexed as

Endothelial CellsMeningitis, BacterialAnimalsEscherichia coliLipopolysaccharidesMiceToll-Like Receptor 4LipopolysaccharidesToll-Like Receptor 4bacterial infectionblood-brain barrierinfectious diseasemeningesmicrobiologymouseneuroscience

Identifiers

PMID37318981
PMCPMC10270687
OpenAlexW4380872421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.