Evidence map›Paper›PMID 37318957›Full record

ReviewChemical reviews2023

The Emerging Role of Raman Spectroscopy as an Omics Approach for Metabolic Profiling and Biomarker Detection toward Precision Medicine.

Gabriel Cutshaw, Saji Uthaman, Nora Hassan, Siddhant Kothadiya, Xiaona Wen, Rizia Bardhan

Abstract readReview
In one paragraph

Review in Chemical reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

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  19. Non-invasive Imaging Techniques: From Histology to In-vivo Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabriel CutshawDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50012, United States.
Saji UthamanDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50012, United States.ORCID 0000-0001-6387-7510
Nora HassanDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50012, United States.
Siddhant KothadiyaDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50012, United States.
Xiaona WenBiologics Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.ORCID 0000-0003-0441-4393
Rizia BardhanDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50012, United States.ORCID 0000-0002-5854-652X

Funding

Developing Multimodal Multiplexed ImmunoPET-Raman Probes to Guide ImmunotherapiesR01EB029756 · NIBIB · IOWA STATE UNIVERSITY · PI BARDHAN, RIZIA · 2020 to 2024
$1.2M
PRADA: Portable Reusable Accurate Diagnostics with nanoAntennas for Multiplexed Biomarker Screening of Preterm LaborR21HD100685 · NICHD · IOWA STATE UNIVERSITY · PI BARDHAN, RIZIA · 2020 to 2021
$423k
NIBIB NIH HHS R01 EB029756NICHD NIH HHS R21 HD100685
6 · The paper itself

Abstract

Omics technologies have rapidly evolved with the unprecedented potential to shape precision medicine. Novel omics approaches are imperative toallow rapid and accurate data collection and integration with clinical information and enable a new era of healthcare. In this comprehensive review, we highlight the utility of Raman spectroscopy (RS) as an emerging omics technology for clinically relevant applications using clinically significant samples and models. We discuss the use of RS both as a label-free approach for probing the intrinsic metabolites of biological materials, and as a labeled approach where signal from Raman reporters conjugated to nanoparticles (NPs) serve as an indirect measure for tracking protein biomarkers

Indexed as

Precision MedicineSpectrum Analysis, RamanBiomarkersMetabolomicsProteomicsBiomarkers

Identifiers

PMID37318957
PMCPMC10626597

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.