Evidence map›Paper›PMID 37318872›Full record

ArticleThe journal of spinal cord medicine2023

Assessment of high-risk opioid use metrics among individuals with spinal cord injury: A brief report.

Nicole D DiPiro, David Murday, James S Krause

Open access · greenAbstract read
In one paragraph

Article in The journal of spinal cord medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicole D DiPiroCollege of Health Professions, Medical University of South Carolina, Charleston, South Carolina, USA.
David MurdayArnold School of Public Health, University of South Carolina, Columbia South Carolina, USA.
James S KrauseCollege of Health Professions, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0001-8129-5389
Medical University of South Carolina · USUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine high-risk opioid prescription metrics among individuals with chronic spinal cord injury (SCI) living in South Carolina.

designCohort Study.

settingTwo statewide population-based databases, an SCI Surveillance Registry and state prescription drug monitoring program (PDMP).

participantsLinked data was obtained for 503 individuals with chronic (>1year-post injury) SCI who were injured in 2013 or 2014 and who survived at least 3 years post-injury.

interventionsNot applicable. MAIN OUTCOME MEASURE(S): Opioid prescription metrics were obtained from the PDMP. Fill data during the period between January 1, 2014 and December 31, 2017 were analyzed to assess high-risk opioid use. Outcomes included: percentage of individuals prescribed chronic opioids, high-dose chronic opioid therapy (daily morphine milligram equivalents (MME) ≥50 and ≥90), and chronic concurrent opioids and benzodiazepines, sedatives, or hypnotics (BSH).

resultsOver half (53%) of the individuals filled an opioid in years 2-3 after injury. Of those, 38% had a concurrent BSH fill during the study period, 76% of which were for benzodiazepines. In any given quarter over the two-year timeframe, over half of the opioid prescriptions were for 60 days or more (chronic opioid prescriptions). Of those, roughly 40% of the individuals had high-dose chronic opioid prescriptions ≥50 MME/d and 25% were ≥90 MME/d. Over 33% had a concurrent BSH prescription for ≥60 days.

conclusionsWhile the number of individuals receiving high-risk opioid prescriptions may not be large, it is a concerning number of prescriptions. The findings suggest a need for more cautious opioid prescribing and monitoring of high-risk use in adults with chronic SCI.

Indexed as

Analgesics, OpioidSpinal Cord InjuriesAdultBenchmarkingBenzodiazepinesCohort StudiesDrug PrescriptionsEndrinHumansPractice Patterns, Physicians'Analgesics, OpioidBenzodiazepinesEndrinMMEAnalgesicsBenzodiazepinesHypnotics and sedativesOpioidPrescription drugsSpinal cord injuries

Identifiers

PMID37318872
PMCPMC10274556
OpenAlexW4310147710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.