Evidence map›Paper›PMID 37318763›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

Fulminant echovirus 11 hepatitis in male non-identical twins in northern Italy, April 2023.

Antonio Piralla, Alessandro Borghesi, Amelia Di Comite, Federica Giardina, Guglielmo Ferrari, Simona Zanette, Tiziana Angelica Figar, Micol Angelini, Camilla Pisoni, Antonino Maria Guglielmo Pitrolo and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Enterovirus infections in children.Pediatric investigation · 2026
    Review
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  7. Review
  8. Neonatal acute liver failure cases with echovirus 11 infections, Japan, August to November 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  9. Article
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  14. Enhanced echovirus 11 genomic surveillance in neonatal infections in Spain following a European alert reveals new recombinant forms linked to severe cases, 2019 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  15. Article
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  19. Genetic Diversity of Human Enterovirus in Kazakhstan, during 2022.International journal of microbiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Antonio PirallaMicrobiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Alessandro BorghesiNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Amelia Di ComiteNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Federica GiardinaDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.
Guglielmo FerrariMicrobiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Simona ZanetteNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Tiziana Angelica FigarNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Micol AngeliniNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Camilla PisoniNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Antonino Maria Guglielmo PitroloMicrobiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Stefania PaolucciMicrobiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Francesca RovidaMicrobiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Isabella PellicioliPaediatric Intensive Care Unit, Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Ezio BonanomiPaediatric Intensive Care Unit, Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Fausto BaldantiMicrobiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Stefano GhirardelloNeonatal Intensive Care Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Policlinico San Matteo Fondazione · ITUniversity of Pavia · ITOspedale Papa Giovanni XXIII · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Echovirus 11 (E11) has recently been associated with a series of nine neonatal cases of severe hepatitis in France. Here, we present severe hepatitis caused by E11 in a pair of twins. In one of the neonates, the clinical picture evolved to fulminant hepatitis. The E11 genome showed 99% nucleotide identity with E11 strains reported in the cases in France. Rapid genome characterisation using next generation sequencing is essential to identify new and more pathogenetic variants.

Indexed as

Echovirus InfectionsHepatitisHepatitis AMassive Hepatic NecrosisEnterovirus B, HumanFranceHumansInfant, NewbornItalyMaleechovirus 11 (E11)enteroviruseshepatitisneonatal infection

Identifiers

PMID37318763
PMCPMC10318938
OpenAlexW4380730430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.