ArticleClinical and experimental nephrology2023
Association between annual variability of potassium levels and prognosis in patients undergoing hemodialysis.
Article in Clinical and experimental nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Dynamic potassium variability (K-CV) as an independent predictor of mortality in maintenance hemodialysis.Renal failure · 2026Article
- Impact of RAASIs on Potassium and Mortality in a Large Cohort of Hemodialysis Patients: Practical Excursus and Comparison Between Traditional Statistics and Machine Learning.Journal of clinical medicine · 2026Article
- Prevalence, practice pattern, and mortality of hyperkalemia in Chinese patients undergoing hemodialysis in the visualize HD study.Scientific reports · 2025Observational
- Strategies for hyperkalemia management in dialysis patients: A systematic review.Open medicine (Warsaw, Poland) · 2025Review
- Associations between serum potassium variability and mortality in patients undergoing maintenance hemodialysis: a retrospective study.Scientific reports · 2024Article
- Hyperkalemia burden and treatment patterns in Chinese patients on hemodialysis: final analysis of a prospective multicenter cohort study (PRECEDE-K).Renal failure · 2024Article
- Seasonal variation of serum potassium in hemodialysis patients: myth or reality? A narrative review of literature.Renal failure · 2024Review
- Effect of banana intake on serum potassium level in patients undergoing maintenance hemodialysis: A randomized controlled trial.International journal of nursing sciences · 2024Article
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7 authors.
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Abstract
backgroundHyperkalemia and hypokalemia are associated with mortality in patients undergoing hemodialysis. However, there are few reports on the association between potassium level fluctuations and mortality. We retrospectively investigated the association between serum potassium level variability and mortality in patients undergoing hemodialysis.
methodsThis study was conducted at a single center. Variability in serum potassium levels was evaluated using the standard deviation of potassium level from July 2011 to June 2012, and its association with prognosis was examined by following up the patients for 5 years. Serum potassium variability was assessed as the coefficient of variation, and the statistical analysis was performed after log transformation.
resultsAmong 302 patients (mean age 64.9 ± 13.3; 57.9% male; and median dialysis vintage 70.5 months [interquartile range, IQR 34-138.3]), 135 died during the observation period (median observation period 5.0 years [2.3-5.0]). Although the mean potassium level was not associated with prognosis, serum potassium level variability was associated with prognosis, even after adjustments for confounding factors such as age and dialysis time (hazard ratio: 6.93, 95% confidence interval [Cl] 1.98-25.00, p = 0.001). After the adjustments, the coefficient of variation of potassium level in the highest tertile (T3) showed a higher relative risk for prognosis than that in T1 (relative risk: 1.98, 95% CI 1.19-3.29, p = 0.01).
conclusionsVariability in serum potassium levels was associated with mortality in patients undergoing hemodialysis. Careful monitoring of potassium levels and their fluctuations is necessary for this patient population.
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