Evidence map›Paper›PMID 37318714›Full record

ArticleDrugs in R&D2023

Bioavailability of Cariban

Paula Saz-Leal, Laura Zamorano-Domínguez, Jesús Frías, Pedro Guerra, Marc Saura-Valls, Ramón Roca-Juanes, Joaquín Nebot-Troyano, Eva García-Aguilar, Tatiana Vilchez, Katia Urso

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drugs in R&D, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06055192 (Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06055192 unknown statusnot on this map

Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022

TypeobservationalSponsorEffik SARan2023 to 2024Enrolled200ConditionsNausea, Vomiting of PregnancyArmsSurvey
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Paula Saz-LealMedical Department, ITF Research Pharma S.L.U., Alcobendas, Spain.ORCID http://orcid.org/0000-0002-6263-4709
Laura Zamorano-DomínguezR&D Department, ITF Research Pharma S.L.U., Alcobendas, Spain.
Jesús FríasClinical Pharmacology Department, La Paz University Hospital, School of Medicine, IdiPAZ, Autonomous University of Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0001-9538-9677
Pedro GuerraClinical Pharmacology Department, La Paz University Hospital, School of Medicine, IdiPAZ, Autonomous University of Madrid, Madrid, Spain.
Marc Saura-VallsInibsa Ginecologia S.A, Barcelona, Spain.
Ramón Roca-JuanesInibsa Ginecologia S.A, Barcelona, Spain.
Joaquín Nebot-TroyanoInibsa Ginecologia S.A, Barcelona, Spain.
Eva García-AguilarMedical Department, ITF Research Pharma S.L.U., Alcobendas, Spain.
Tatiana VilchezMedical Department, ITF Research Pharma S.L.U., Alcobendas, Spain.
Katia UrsoR&D Department, ITF Research Pharma S.L.U., Alcobendas, Spain. k.urso@italfarmacogroup.com.ORCID http://orcid.org/0000-0003-0141-4056
Universidad Autónoma de Madrid · ESBP (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNausea and vomiting is a very prevalent condition during pregnancy. Combination of doxylamine and pyridoxine is placed as first-line pharmacological option for its treatment in most clinical guidelines. Among different release forms available, Cariban

objectivesIn the present study, we aimed to characterize the bioavailability performance of Cariban

methodsAn in vitro dissolution test was performed to evaluate the release profile of Cariban

resultsCariban

conclusionCariban

Indexed as

AntiemeticsPregnancy ComplicationsAdultBiological AvailabilityCapsulesDelayed-Action PreparationsDoxylamineDrug CombinationsFemaleHumansNauseaPregnancyPyridoxineVomitingAntiemeticsCapsulesDelayed-Action PreparationsDoxylamineDrug CombinationsPyridoxine

Identifiers

PMID37318714
PMCPMC10293548
OpenAlexW4380730649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.