Evidence map›Paper›PMID 37318688›Full record

ArticleApplied biochemistry and biotechnology2024

Analysis of Correlation Between LncRNA TDRG1 Expression and its Prognosis in Cervical Carcinoma Tissues.

Amal Ezzat Abd El-Lateef, Adel Galal Ahmed El-Shemi, Raafat Abdel Moneim Hassanein, Mohammad Shahid Iqbal, Shatha Abdullah Albloshi

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Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Amal Ezzat Abd El-LateefDepartment of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm-Alqura University, Mecca, Saudi Arabia. damalezzat@yahoo.com.
Adel Galal Ahmed El-ShemiDepartment of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm-Alqura University, Mecca, Saudi Arabia.
Raafat Abdel Moneim HassaneinDepartment of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm-Alqura University, Mecca, Saudi Arabia.
Mohammad Shahid IqbalDepartment of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm-Alqura University, Mecca, Saudi Arabia.
Shatha Abdullah AlbloshiCollege of Medicine, King Abdulaazzi Bin University, Riyadh, Saudi Arabia. Abuam004@gmail.com.
Umm al-Qura University · SAAssiut University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore and analyze the correlation between LncRNA TDRG1 expression degree and the prognosis of cervical carcinoma tissues. The cervical cancer tissues and para-carcinoma tissues of 106 patients with cervical carcinoma surgically removed in our hospital were chosen as specimens. LncRNA TDRG1 expression in cervical carcinoma tissues and para-carcinoma tissues was inspected by real-time fluorescence quantitative PCR, and the correlation between LncRNA TDRG1 and the clinicopathological parameters and disease prognosis was analyzed. The relative expression of LncRNA TDRG1 in cervical carcinoma tissues was critically gone up (P < 0.05) compared to para-carcinoma tissues. The relative expression of LncRNA TDRG1 in cervical carcinoma was correlated with FIGO staging, lymph node metastasis, infiltrating depth of cervical basal, and the differentiation of cancer cells (P < 0.05). According to the results of the Kaplan-Meier curve and Log-rank test, the overall survival conditions of subjects with low-lncRNA TDRG1 were superior to that of those with high-lncRNA TDRG1 expression (P < 0.05). The expression of LncRNA TDRG1 in cervical carcinoma tissues and the clinicopathological features in predicting the overall survival (OS) in sufferers with cervical carcinoma were investigated by the Cox regression model. LncRNA TDRG1 expression in cervical carcinoma tissues is tightly associated with the progression and prognosis of cervical carcinoma, which may be a latent biological indicator for clinical diagnosis and prognosis of cervical carcinoma.

Indexed as

RNA, Long NoncodingUterine Cervical NeoplasmsBiomarkers, TumorCell DifferentiationFemaleGene Expression Regulation, NeoplasticHumansPrognosisBiomarkers, TumorRNA, Long NoncodingTDRG1 long non-coding RNA, humanCervical carcinoma tissuesClinical prognosisLncRNA TDRG1Pathological features

Identifiers

PMID37318688
OpenAlexW4380607970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.