Evidence map›Paper›PMID 37318453›Full record

ArticleThe Journal of cell biology2023

RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles.

Annika Kratzel, Volker Thiel

Abstract readComment
In one paragraph

Article in The Journal of cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Annika KratzelInstitute of Virology and Immunology (IVI) , Bern, Switzerland.
Volker ThielInstitute of Virology and Immunology (IVI) , Bern, Switzerland.ORCID 0000-0002-5783-0887

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 depends on host proteins for successful replication. In this issue, Williams et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202203060) report that the ER membrane-modulating proteins RTN3 and RTN4 are required for the formation of SARS-CoV-2 replication organelles via direct interaction with viral proteins NSP3 and NSP4.

Indexed as

Carrier ProteinsMembrane ProteinsNerve Tissue ProteinsNogo ProteinsSARS-CoV-2Virus ReplicationCoronavirus Papain-Like ProteasesCOVID-19Endoplasmic ReticulumHumansViral Nonstructural ProteinsCarrier ProteinsCoronavirus Papain-Like ProteasesMembrane ProteinsNerve Tissue ProteinsNogo ProteinsORF1ab polyprotein, SARS-CoV-2papain-like protease, SARS-CoV-2RTN3 protein, humanRTN4 protein, humanViral Nonstructural Proteins

Identifiers

PMID37318453
PMCPMC10274048

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.