Evidence map›Paper›PMID 37318023›Full record

ArticleJournal of the American Heart Association2023

Comparative Outcomes of Interventions for Femoropopliteal Chronic Total Occlusion Versus Non-Chronic Total Occlusion Lesions From the Multicenter XLPAD Registry.

Shirling Tsai, Yulun Liu, Lawrence Hoang, Michael Vu, Hua Lu, Bala Ramanan, David Fernandez Vazquez, Zachary Rosol, Sameh Sayfo, Mohamad Amer Alaiti and 4 more

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01904851 (Multi-Center Registry Comparing Stent and Non-Stent Based Interventional Outcomes for Patients With Peripheral Arterial Disease), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01904851 recruitingnot on this map

Multi-Center Registry Comparing Stent and Non-Stent Based Interventional Outcomes for Patients With Peripheral Arterial Disease

Typeobservational_patient_registrySponsorBaylor Research InstituteRan2013 to 2033Enrolled14,000ConditionsPeripheral Arterial Disease
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Peripheral artery disease.Nature reviews. Disease primers · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Shirling TsaiNorth Texas Veterans Affairs Health Care Systems Dallas TX USA.ORCID 0000-0003-0269-2605
Yulun LiuUniversity of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0003-3541-1814
Lawrence HoangNorth Texas Veterans Affairs Health Care Systems Dallas TX USA.
Michael VuNorth Texas Veterans Affairs Health Care Systems Dallas TX USA.
Hua LuNorth Texas Veterans Affairs Health Care Systems Dallas TX USA.ORCID 0009-0003-0882-7344
Bala RamananNorth Texas Veterans Affairs Health Care Systems Dallas TX USA.ORCID 0000-0003-1319-5903
David Fernandez VazquezNorth Texas Veterans Affairs Health Care Systems Dallas TX USA.ORCID 0000-0003-4306-1447
Zachary RosolBaylor Scott and White Hospital Dallas TX USA.
Sameh SayfoBaylor Scott and White Hospital Plano TX USA.
Mohamad Amer AlaitiMedical City Plano Plano TX USA.
Panagiotis KoutakisBaylor University Waco TX USA.ORCID 0000-0002-8352-5667
Emmanouil S BrilakisMinnesota Heart Institute Minneapolis MN USA.ORCID 0000-0001-9416-9701
Mehdi H ShishehborUniversity Hospital Harrington Heart and Vascular Institute Cleveland OH USA.ORCID 0000-0002-4888-2431
Subhash BanerjeeNorth Texas Veterans Affairs Health Care Systems Dallas TX USA.ORCID 0000-0003-0863-7914
VA North Texas Health Care System · USBaylor Medical Center at Garland · USBaylor University · USMinneapolis Heart Institute Foundation · USPlano Cancer Institute · USThe University of Texas Southwestern Medical Center · USUniversity Hospitals Cleveland Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Endovascular intervention of femoropopliteal chronic total occlusions (CTOs) is technically more complex. However, there is lack of comparative analysis between CTO and non-CTO femoropopliteal interventions. Methods and Results We report procedural details and outcomes of patients treated for femoropopliteal CTO and non-CTO lesions in the XLPAD (Excellence in Peripheral Artery Disease) registry (NCT01904851) between 2006 and 2019. Primary outcomes were procedural success and 1-year major adverse limb events, a composite of all-cause death, target limb revascularization, or major amputation. Analysis included 2895 patients (CTO: n=1516 patients; non-CTO: n=1379 patients) with 3658 lesions (CTO: n=1998 lesions; non-CTO: n=1660 lesions). Conventional balloon angioplasty (20.86% versus 33.48%,

Indexed as

Peripheral Arterial DiseasePopliteal ArteryChronic DiseaseFemoral ArteryHumansRegistriesTreatment OutcomeVascular Patencychronic total occlusionfemoropopliteal diseaseoutcomes analysisperipheral artery diseaseprospective registry

Identifiers

PMID37318023
PMCPMC10356025
OpenAlexW4380730683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.