ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2023
The feasibility of novel point-of-care diagnostics for febrile illnesses at health centres in Southeast Asia: a mixed-methods study.
Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Operational evaluation of the deployment of Malaria/CRP Duo and Dengue Duo rapid diagnostic tests for the management of febrile illness by village malaria workers in rural Cambodia.BMC infectious diseases · 2025Article
- Malaria elimination challenges in countries approaching the last mile: a discussion among regional stakeholders.Malaria journal · 2024Review
- Article
- Expanding the roles of community health workers to sustain programmes during malaria elimination: a meeting report on operational research in Southeast Asia.Malaria journal · 2024Article
- Expanding the roles of malaria post workers in Thailand: A qualitative study of stakeholder perspectives.PLOS global public health · 2024Article
- Expanded roles of community health workers to sustain malaria services in the Asia-Pacific: A landscaping survey.PLOS global public health · 2024Article
- Rethinking village malaria workers in Cambodia: Perspectives from the communities, programme managers, and international stakeholders.PLOS global public health · 2024Article
- Comparing the roles of community health workers for malaria control and elimination in Cambodia and Tanzania.BMJ global health · 2023Review
Corrections and comments
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Authors and funding
18 authors at 6 institutions in 5 countries.
Funding
Abstract
backgroundThe decline of malaria in Southeast Asia means other causes of fever are increasingly relevant, but often undiagnosed. The objective of this study was to assess the feasibility of point-of-care tests to diagnose acute febrile illnesses in primary care settings.
methodsA mixed-methods study was conducted at nine rural health centres in western Cambodia. Workshops introduced health workers to the STANDARD(TM) Q Dengue Duo, STANDARD(TM) Q Malaria/CRP Duo and a multiplex biosensor detecting antibodies and/or antigens of eight pathogens. Sixteen structured observation checklists assessed users' performances and nine focus group discussions explored their opinions.
resultsAll three point-of-care tests were performed well under assessment, but sample collection was difficult for the dengue test. Respondents expressed that the diagnostics were useful and could be integrated into routine clinical care, but were not as convenient to perform as standard malaria rapid tests. Health workers recommended that the most valued point-of-care tests would directly inform clinical management (e.g. a decision to refer a patient or to provide/withhold antibiotics).
conclusionsDeployment of new point-of-care tests to health centres could be feasible and acceptable if they are user-friendly, selected for locally circulating pathogens and are accompanied by disease-specific education and simple management algorithms.
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Registered trials
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