Evidence map›Paper›PMID 37317248›Full record

ArticleMicroorganisms2023

Targeted Mutations Produce Divergent Characteristics in Pedigreed Sake Yeast Strains.

Norapat Klinkaewboonwong, Shinsuke Ohnuki, Tomoya Chadani, Ikuhisa Nishida, Yuto Ushiyama, Saki Tomiyama, Atsuko Isogai, Tetsuya Goshima, Farzan Ghanegolmohammadi, Tomoyuki Nishi and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Norapat KlinkaewboonwongDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.
Shinsuke OhnukiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.
Tomoya ChadaniDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.
Ikuhisa NishidaSakeology Center, Niigata University, 2-8050, Ikarashi, Niigata 950-2181, Japan.ORCID 0000-0001-7873-3237
Yuto UshiyamaSakeology Course, Graduate School of Science and Technology, Niigata University, 2-8050, Ikarashi, Niigata 950-2181, Japan.
Saki TomiyamaSakeology Course, Graduate School of Science and Technology, Niigata University, 2-8050, Ikarashi, Niigata 950-2181, Japan.
Atsuko IsogaiNational Research Institute of Brewing, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Tetsuya GoshimaNational Research Institute of Brewing, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Farzan GhanegolmohammadiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.ORCID 0000-0001-5217-0878
Tomoyuki NishiSake Research Center, Asahi Sake Brewing Co., Ltd., Nagaoka, Niigata 949-5494, Japan.
Katsuhiko KitamotoDepartment of Pharmaceutical and Medical Business Sciences, Nihon Pharmaceutical University, Bunkyo-ku, Tokyo 113-0034, Japan.
Takeshi AkaoNational Research Institute of Brewing, Higashi-Hiroshima, Hiroshima 739-0046, Japan.
Dai HirataSakeology Center, Niigata University, 2-8050, Ikarashi, Niigata 950-2181, Japan.
Yoshikazu OhyaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.ORCID 0000-0003-0837-1239
The University of Tokyo · JPHiroshima University · JPNiigata University · JPMassachusetts Institute of Technology · USNational Research Institute of Brewing · JPNihon Pharmaceutical University · JP

Funding

an annual research fund from the National Research Institute of Brewin an annual research fundInstitute for Fermentation, Osaka (IFO) Laboratory grant IFOJapan Society for the Promotion of Science 20K06584Japan Society for the Promotion of Science 21K05377Japan Society for the Promotion of Science 22H02216NAGAI N-S Promotion Foundation for Science of Perception Research Grant NAGAI N-S
6 · The paper itself

Abstract

Modification of the genetic background and, in some cases, the introduction of targeted mutations can play a critical role in producing trait characteristics during the breeding of crops, livestock, and microorganisms. However, the question of how similar trait characteristics emerge when the same target mutation is introduced into different genetic backgrounds is unclear. In a previous study, we performed genome editing of

Indexed as

CRISPR/Cas9FAS2genome editingSaccharomyces cerevisiaesake yeast

Identifiers

PMID37317248
PMCPMC10222758
OpenAlexW4380730217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.