Evidence map›Paper›PMID 37317226›Full record

ReviewMicroorganisms2023

Metabolic Engineering of Model Microorganisms for the Production of Xanthophyll.

Nan Wang, Huakang Peng, Caifeng Yang, Wenfang Guo, Mengqi Wang, Gangqiang Li, Dehu Liu

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Carotenoid Yeasts and Their Application Potential.Foods (Basel, Switzerland) · 2025
    Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nan WangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Huakang PengBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.ORCID 0000-0003-3991-9375
Caifeng YangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Wenfang GuoBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Mengqi WangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Gangqiang LiBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Dehu LiuBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Chinese Academy of Agricultural Sciences · CN

Funding

Foundation of Hainan Yazhou Bay Seed Lab B21HJ0212National Natural Science Foundation of China 31901661
6 · The paper itself

Abstract

Xanthophyll is an oxidated version of carotenoid. It presents significant value to the pharmaceutical, food, and cosmetic industries due to its specific antioxidant activity and variety of colors. Chemical processing and conventional extraction from natural organisms are still the main sources of xanthophyll. However, the current industrial production model can no longer meet the demand for human health care, reducing petrochemical energy consumption and green sustainable development. With the swift development of genetic metabolic engineering, xanthophyll synthesis by the metabolic engineering of model microorganisms shows great application potential. At present, compared to carotenes such as lycopene and β-carotene, xanthophyll has a relatively low production in engineering microorganisms due to its stronger inherent antioxidation, relatively high polarity, and longer metabolic pathway. This review comprehensively summarized the progress in xanthophyll synthesis by the metabolic engineering of model microorganisms, described strategies to improve xanthophyll production in detail, and proposed the current challenges and future efforts needed to build commercialized xanthophyll-producing microorganisms.

Indexed as

biosynthetic pathwaymetabolic engineeringmodel microorganismsxanthophyll

Identifiers

PMID37317226
PMCPMC10223009
OpenAlexW4380729851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.