Evidence map›Paper›PMID 37316257›Full record

ArticleBMJ mental health2023

Predicting outcomes at the individual patient level: what is the best method?

Qiang Liu, Edoardo Giuseppe Ostinelli, Franco De Crescenzo, Zhenpeng Li, Anneka Tomlinson, Georgia Salanti, Andrea Cipriani, Orestis Efthimiou

Open access · diamondAbstract read
In one paragraph

Article in BMJ mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Qiang LiuDepartment of Psychiatry, University of Oxford, Oxford, UK qiang.liu@bristol.ac.uk.ORCID 0000-0001-7531-4459
Edoardo Giuseppe OstinelliDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID 0000-0002-8717-0832
Franco De CrescenzoDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID 0000-0002-2478-7763
Zhenpeng LiDepartment of Psychiatry, University of Oxford, Oxford, UK.ORCID 0000-0001-9431-258X
Anneka TomlinsonDepartment of Psychiatry, University of Oxford, Oxford, UK.
Georgia SalantiInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.ORCID 0000-0002-3830-8508
Andrea Cipriani *Department of Psychiatry, University of Oxford, Oxford, UK.ORCID 0000-0001-5179-8321
Orestis Efthimiou *Oxford Precision Psychiatry Lab, NIHR Oxford Health Biomedical Research Centre, Oxford, UK.
University of Oxford · GBOxford Health NHS Foundation Trust · GBUniversity of Bern · CHUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWhen developing prediction models, researchers commonly employ a single model which uses all the available data (

methodsWe used primary care data collected in general practices in the UK. Using 31 predefined baseline variables, we aimed to predict the severity of depressive symptoms, measured by Patient Health Questionnaire-9, 60 days after initiation of antidepressant treatment. Following the similarity-based approach, we used

resultsWe analysed data from 16 384 patients. The end-to-end approach resulted in an MAE of 4.64 and R

conclusionsThe end-to-end and the similarity-based model yielded comparable performance. Due to its simplicity, the end-to-end approach can be favoured when using demographic and clinical data to build prediction models on pharmacological treatments for depression.

Indexed as

DepressionAdultFemaleGeneral PracticeHumansMaleMiddle AgedMood DisordersPatient Health QuestionnairePredictive Value of TestsSeverity of Illness IndexDepression & mood disorders

Identifiers

PMID37316257
PMCPMC10277128
OpenAlexW4380685061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.