ArticleBritish journal of sports medicine2023
Healing of acute anterior cruciate ligament rupture on MRI and outcomes following non-surgical management with the Cross Bracing Protocol.
Article in British journal of sports medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Conservative Treatment With Blood Flow Restriction With Standard Management in Total ACL Rupture. "Randomized Clinical Trial"
Effects of Cross Bracing Protocol With And Without Dynamic Neuromuscular Stabilization Training on Functional Movements in Athletes With Acute Anterior Cruciate Ligament Injury
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- No Difference in Return-to-Sport Rate or Activity Level in People with Anterior Cruciate Ligament (ACL) Injury Managed with ACL Reconstruction or Rehabilitation Alone: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- MRI deep learning models for assisted diagnosis of knee pathologies: a systematic review.European radiology · 2025Pooled it
- Non-surgical treatment of anterior cruciate ligament tears with percutaneous bone marrow concentrate and platelet products versus exercise therapy: a randomized-controlled, crossover trial with 2-year follow-up.BMC musculoskeletal disorders · 2025Trial
- Factors Influencing Consultant Knee Surgeons' Decision Making in Anterior Cruciate Ligament (ACL) Injury Management in Athletes: An International Delphi Study.Sports medicine (Auckland, N.Z.) · 2026Article
- Magnetic Resonance Imaging Assessment of Bridge-Enhanced ACL Restoration: An Imaging Atlas of Morphological Features and Healing Trajectories.Orthopaedic journal of sports medicine · 2026Article
- Non-Operative Management of a Complete ACL Rupture With the Cross-Bracing Protocol in an Elite Australian Rules Football Athlete.Clinical case reports · 2026Article
- Conservative treatment using blood flow restriction and brace in individuals with complete anterior cruciate ligament rupture: protocol for a randomised clinical trial.Journal of orthopaedic surgery and research · 2025Article
- From Past to Future: Emergent Concepts of Anterior Cruciate Ligament Surgery and Rehabilitation.Journal of clinical medicine · 2025Review
- Phytochemical analysis and antimicrobial activity of Ganoderma lucidum against selected bacteria and fungi of medical importance.Scientific reports · 2025Article
- Comparative efficacy of different lengths of anterior cruciate ligament stump during reconstruction with peroneus longus tendon.BMC surgery · 2025Article
- ACL Pacinian mechanoreceptors: Conceptualizing a vasoregulatory microtrauma healing function.Journal of experimental orthopaedics · 2025Article
- Surgical Stabilization Results in Superior Clinical Outcome, Lower Recurrent Instability, and Reduced Risk of Meniscal Tears Relative to Nonoperative Treatment of ACL Rupture: A 3-Year Prospective Controlled Cohort Study.Orthopaedic journal of sports medicine · 2025Article
- Micro-needle knife combined with intra-articular and subchondral bone injection of platelet-rich plasma benefits moderate to advanced knee osteoarthritis.American journal of translational research · 2025Article
- Deciding Between ACL Reconstruction, Repair, and Conservative Treatment in Young Athletes: A Systematic Narrative Review.Open access journal of sports medicine · 2025Review
- Posttraumatic osteoarthritis after athletic knee injury: A narrative review of diagnostic imaging strategies.PM & R : the journal of injury, function, and rehabilitation · 2025Review
- Extracorporeal Shock Wave and Melatonin Alleviate Joint Capsule Fibrosis after Knee Trauma in Rats by Regulating Autophagy.Current molecular medicine · 2025Article
- Acute anterior cruciate ligament injuries can be repaired through conservative treatment with early protective motion: a single-group cohort study.BMJ open sport & exercise medicine · 2025Article
- Addressing rising knee injury and surgery rates with real-word data; the need for a clinical knee injury registry.JSAMS plus · 2024Article
- Regenerative Anterior Cruciate Ligament Healing in Youth and Adolescent Athletes: The Emerging Age of Recovery Science.Journal of functional morphology and kinesiology · 2024Review
- The Role of MRI Scan in Sports-Related Anterior Cruciate Ligament Injuries: A Case Report-Based Literature Review.Cureus · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInvestigate MRI evidence of anterior cruciate ligament (ACL) healing, patient-reported outcomes and knee laxity in patients with acute ACL rupture managed non-surgically with the Cross Bracing Protocol (CBP).
methodsEighty consecutive patients within 4 weeks of ACL rupture were managed with CBP (knee immobilisation at 90° flexion in brace for 4 weeks, followed by progressive increases in range-of-motion until brace removal at 12 weeks, and physiotherapist-supervised goal-oriented rehabilitation). MRIs (3 months and 6 months) were graded using the ACL OsteoArthritis Score (ACLOAS) by three radiologists. Mann-Whitney U tests compared Lysholm Scale and ACL quality of life (ACLQOL) scores evaluated at median (IQR) of 12 months (7-16 months) post-injury, and χ
resultsParticipants were aged 26±10 years at injury, 39% were female, 49% had concomitant meniscal injury. At 3 months, 90% (n=72) had evidence of ACL healing (ACLOAS grade 1: 50%; grade 2: 40%; grade 3: 10%). Participants with ACLOAS grade 1 reported better Lysholm Scale (median (IQR): 98 (94-100) vs 94 (85-100)) and ACLQOL (89 (76-96) vs 70 (64-82)) scores, compared with ACLOAS grades 2-3. More participants with ACLOAS grade 1 had normal 3-month knee laxity (100% vs 40%) and returned to pre-injury sport (92% vs 64%), compared with participants with an ACLOAS grades 2-3. Eleven patients (14%) re-injured their ACL.
conclusionAfter management of acute ACL rupture with the CBP, 90% of patients had evidence of healing on 3-month MRI (continuity of the ACL). More ACL healing on 3-month MRI was associated with better outcomes. Longer-term follow-up and clinical trials are needed to inform clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.