ArticleGastroenterology2023
Prevalence and Associated Factors of Bloating: Results From the Rome Foundation Global Epidemiology Study.
Article in Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07103772 (Effect of Consuming a Nutraceutical Composition Based on Pineapple and Natural Extracts on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Consuming a Nutraceutical Composition Based on Pineapple and Natural Extracts on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- European Consensus on Functional Bloating and Abdominal Distension-An ESNM/UEG Recommendations for Clinical Management.United European gastroenterology journal · 2025Guideline
- Effect of herbal formula based on rosa damascena on functional bloating severity in older adults: a pilot double-blind randomized controlled trial.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Trial
- A Randomized, Placebo-Controlled Trial Evaluating Multi-Species Synbiotic Supplementation for Bloating, Gas, and Abdominal Discomfort.Nutrients · 2026Trial
- The Effectiveness of Plecanatide for Treating Constipation and Bloating in Patients Aged 18 to 40 Years With Irritable Bowel Syndrome: Utilization of a New Composite Trisymptom Endpoint.Journal of gastroenterology and hepatology · 2025Trial
- Constipation with bloating: a clinical approach to evaluation and management.Annals of medicine · 2026Review
- Irritable bowel syndrome.Nature reviews. Disease primers · 2026Review
- A distinct gastrointestinal symptom profile characterizes clinically relevant fatigue in systemic sclerosis.Clinical rheumatology · 2026Article
- Physicochemical, Bioactive, and Clinical Evaluation of Blueberry-Enriched Kombucha as a Functional Beverage.Journal of food science · 2026Article
- Association of Carbohydrate Consumption and Bloating in Individuals With Different FTO Genotypes.Molecular nutrition & food research · 2026Article
- Bloating, Visible Abdominal Distension, and Other Intestinal Gas-Related Symptoms in Irritable Bowel Syndrome and Functional Dyspepsia.United European gastroenterology journal · 2026Article
- Bali Chronic Constipation Roundtable Report: Chronic Constipation Management in Asia.Journal of neurogastroenterology and motility · 2026Article
- Endoscopic findings in patients with chronic bloating/abdominal distension and the effect of the transition from the Rome III to Rome IV criteria: a multicenter cross-sectional study.BMC gastroenterology · 2026Article
- Gastrointestinal symptoms in adults with Fabry disease and their associations with physical and mental health.BMC gastroenterology · 2025Article
- Abdominal Bloating and Distension: Common Symptoms but Limited Evidence.United European gastroenterology journal · 2025Article
- Prevalence of Upper Gastrointestinal Symptoms and Gastric Dysrhythmias in Diabetic and Non-Diabetic Indian Populations: A Real-World Retrospective Analysis from Electrogastrography Data.Diagnostics (Basel, Switzerland) · 2025Article
- Comparing biofeedback device vs diaphragmatic breathing for bloating relief: A randomized controlled trial.Open medicine (Warsaw, Poland) · 2025Article
- The Relationship Between Nutrition Impact Symptoms, Intake Status, and Systemic Inflammation for Cancer Patients.Cancer management and research · 2025Article
- Leaky Gut Syndrome: Myths and Management.Gastroenterology & hepatology · 2024Article
- Safety and Tolerability of Microbial Inulinase Supplementation in Healthy Adults: A Randomized, Placebo-Controlled Trial.Gastro hep advances · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
BACKGROUND &
aimsBloating is a common symptom in the general population and among disorders of gut-brain interaction, although its prevalence has not been well characterized. The aim of this study was to report the prevalence of bloating as a symptom in the worldwide population and to identify factors associated with this symptom in the general population.
methodsRome Foundation Global Epidemiology Study internet survey data were analyzed. After excluding respondents with potential organic causes of bowel symptoms, the current analysis included 51,425 individuals in 26 countries. Data included diet, medical history, quality of life, and Rome IV diagnostic questions. Presence of bloating was defined as experiencing bloating at least once per week for the last 3 months. Descriptive statistics estimated prevalence by country, region, and disorder of gut-brain interaction diagnosis. Logistic regression evaluated predictors of bloating.
resultsNearly 18% of the global study population reported bloating (ranging from 11% in East Asia to 20% in Latin America). Prevalence decreased with age and women were approximately twice as likely as men to report bloating. More than one-half of respondents who reported weekly epigastric pain (71.39%), nausea (59.7%), or abdominal pain (61.69%) also reported bloating at least once per week. In logistic regression, the strongest associations were with abdominal pain (odds ratio, 2.90) and epigastric pain (odds ratio, 2.07).
conclusionsBloating is common throughout the world. Nearly 18% of the general population experience bloating at least once per week. Reported bloating prevalence is lower in older age groups, most common in women, and strongly associated with abdominal pain.
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