ArticleEnvironmental research2023
Prenatal ambient air pollutant mixture exposure and neurodevelopment in urban children in the Northeastern United States.
Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Prenatal Exposure to Nitrogen Dioxide, Fine Particulates, and Ozone in Relation to Child Behavior: The Environmental Influences on Child Health Outcomes Cohort.Environmental science & technology · 2026Article
- Ambient air pollution during pregnancy and offspring cerebral palsy.Environment international · 2026Article
- Association between early life constituent-specific PMBMC medicine · 2026Article
- Associations of prenatal fine particulate matter mixtures with neurodevelopmental outcomes in early childhood: component- and source-specific insights.Particle and fibre toxicology · 2026Article
- Differential impacts of short-term PMScience China. Life sciences · 2026Article
- Mixture analysis identifies ozone as driving factor for child asthma symptoms.The journal of allergy and clinical immunology. Global · 2025Article
- The Association of Prenatal Dietary Factors with Child Autism Diagnosis and Autism-Related Traits Using a Mixtures Approach: Results from the Environmental Influences on Child Health Outcomes Cohort.The Journal of nutrition · 2025Article
- Structured Bayesian Regression Tree Models for Estimating Distributed Lag Effects: The R Package dlmtree.The R journal · 2025Article
- Fetal development and the air pollution exposome: an integrative perspective of health pathways.Frontiers in cellular neuroscience · 2025Article
- The protracted neurotoxic consequences in mice of developmental exposures to inhaled iron nanoparticles alone or in combination with SOFrontiers in behavioral neuroscience · 2025Article
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- Pre-pregnancy ozone and ultrafine particulate matter exposure during second year of life associated with decreased cognitive and adaptive functioning at aged 2-5 years.Environmental research · 2024Article
- A bibliometric analysis of research on the health impacts of ozone air pollution.Environmental science and pollution research international · 2024Review
- Asthma and Environmental Exposures to Phenols, Polycyclic Aromatic Hydrocarbons, and Phthalates in Children.Current environmental health reports · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundStudies of prenatal air pollution (AP) exposure on child neurodevelopment have mostly focused on a single pollutant. We leveraged daily exposure data and implemented novel data-driven statistical approaches to assess effects of prenatal exposure to a mixture of seven air pollutants on cognitive functioning in school-age children from an urban pregnancy cohort.
methodsAnalyses included 236 children born at ≥37 weeks gestation. Maternal prenatal daily exposure levels for nitrogen dioxide (NO
resultsMothers were primarily ethnic minorities (81% Hispanic and/or black) reporting ≤12 years of education (68%). Prenatal AP mixture (per unit increase in WQS estimated AP index) was associated with decreased WRAML-2 general memory (GM; β = -0.64, 95%CI = -1.40, 0.00) and memory-related attention/concentration (AC; β = -1.03, 95%CI = -1.78, -0.27) indices, indicating poorer memory functioning, as well as increased CPT-II omission errors (OE; β = 1.55, 95%CI = 0.34, 2.77), indicating increased attention problems. When stratified by sex, association with AC index was significant among girls, while association with OE was significant among boys. Traffic-related pollutants (NO
conclusionsPrenatal exposure to an AP mixture was associated with child neurocognitive outcomes in a sex- and domain-specific manner.
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