Evidence map›Paper›PMID 37315328›Full record

ArticleJournal of medicinal chemistry2023

First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations.

Avinash H Bansode, Naresh Damuka, Nagaraju Bashetti, Krishna Kumar Gollapelli, Ivan Krizan, Bhuvanachandra Bhoopal, Mack Miller, Shanmukha Kumar Jv, Christopher T Whitlow, Donald McClain and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. [Pharmacological reports : PR · 2025
    Article
  4. Diagnostic and Therapeutic Radiopharmaceuticals: A "Hot" Topic.ACS pharmacology & translational science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Avinash H BansodeDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.
Naresh DamukaDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.
Nagaraju BashettiDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Vijayawada, 522302 Andhra Pradesh, India.
Krishna Kumar GollapelliDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.
Ivan KrizanDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.
Bhuvanachandra BhoopalDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID 0000-0002-2129-009X
Mack MillerDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.
Shanmukha Kumar JvDepartment of Chemistry, Koneru Lakshmaiah Education Foundation, Vijayawada, 522302 Andhra Pradesh, India.
Christopher T WhitlowDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.
Donald McClainDepartment of Endocrinology, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, United States.
Tao MaDepartment of Internal Medicine-Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, United States.
Matthew J JorgensenDepartment of Comparative Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina 27157, United States.
Kiran Kumar Solingapuram SaiDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, United States.ORCID 0000-0002-6442-5169
Wake Forest University · USKoneru Lakshmaiah Education Foundation · IN

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Vervet Research Colony as a Biomedical ResourceP40OD010965 · OD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Matthew Jorgensen · 2012 to 2026
$14.6M
NCATS NIH HHS UL1 TR001420NIH HHS P40 OD010965
6 · The paper itself

Abstract

G-protein-coupled receptor 119 (GPR119) has emerged as a promising target for treating type 2 diabetes mellitus. Activating GPR119 improves glucose homeostasis, while suppressing appetite and weight gain. Measuring GPR119 levels

Indexed as

Diabetes Mellitus, Type 2Fluorine RadioisotopesHumansLigandsPositron-Emission TomographyRadiochemistryReceptors, G-Protein-CoupledTissue DistributionFluorine RadioisotopesGPR119 protein, humanLigandsReceptors, G-Protein-Coupled

Identifiers

PMID37315328
PMCPMC10999001
OpenAlexW4380563835

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.