Evidence map›Paper›PMID 37315144›Full record

ArticleScience advances2023

CD62L expression marks SARS-CoV-2 memory B cell subset with preference for neutralizing epitopes.

Taishi Onodera, Nicolas Sax, Takashi Sato, Yu Adachi, Ryutaro Kotaki, Takeshi Inoue, Ryo Shinnakasu, Takayuki Nakagawa, Shuetsu Fukushi, Tommy Terooatea and 15 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Polarization of the memory B-cell response.Journal of leukocyte biology · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 7 institutions in 1 country.

Taishi OnoderaResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0002-7079-3339
Nicolas SaxKOTAI Biotechnologies Inc., Osaka, Japan.ORCID 0000-0003-3241-4737
Takashi SatoTokyo Shinagawa Hospital, Tokyo, Japan.ORCID 0000-0002-2676-3781
Yu AdachiResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0002-8573-987X
Ryutaro KotakiResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0001-7965-1671
Takeshi InoueLaboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.ORCID 0000-0002-9972-6105
Ryo ShinnakasuLaboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.
Takayuki NakagawaShionogi & Co. Ltd., Osaka, Japan.ORCID 0000-0002-6247-3191
Shuetsu FukushiDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan.
Tommy TerooateaKOTAI Biotechnologies Inc., Osaka, Japan.ORCID 0000-0001-9248-3342
Mai YoshikawaShionogi & Co. Ltd., Osaka, Japan.
Keisuke TonouchiResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.
Takaki NagakuraResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0002-1204-4815
Saya MoriyamaResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0003-2057-9198
Takayuki MatsumuraResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0003-1760-3484
Masanori IsogawaResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0001-8730-4303
Kazutaka TeraharaResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0001-9876-4356
Tomohiro TakanoResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0003-4267-1147
Lin SunResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.
Ayae NishiyamaResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.
Shinnya OmotoShionogi & Co. Ltd., Osaka, Japan.ORCID 0000-0002-2730-3912
Masaharu ShinkaiTokyo Shinagawa Hospital, Tokyo, Japan.ORCID 0000-0002-4012-2518
Tomohiro KurosakiLaboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.ORCID 0000-0002-6352-304X
Kazuo YamashitaKOTAI Biotechnologies Inc., Osaka, Japan.ORCID 0000-0002-7825-4719
Yoshimasa TakahashiResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.ORCID 0000-0001-6342-4087
National Institute of Infectious Diseases · JPShionogi (Japan) · JPTagCyx Biotechnologies (Japan) · JPNew Tokyo Hospital · JPThe University of Osaka · JPOsaka International Cancer Institute · JPWaseda University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2-neutralizing antibodies primarily target the spike receptor binding domain (RBD). However, B cell antigen receptors (BCRs) on RBD-binding memory B (B

Indexed as

B-Lymphocyte SubsetsCOVID-19L-SelectinAntibodies, NeutralizingAntibodies, ViralEpitopesHumansSARS-CoV-2Antibodies, NeutralizingAntibodies, ViralEpitopesL-Selectin

Identifiers

PMID37315144
PMCPMC10266721
OpenAlexW4380605852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.