ArticleLangmuir : the ACS journal of surfaces and colloids2023
α-Amino Acids as Reducing and Capping Agents in Gold Nanoparticles Synthesis Using the Turkevich Method.
Article in Langmuir : the ACS journal of surfaces and colloids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Biosynthesis of Silver Nanoparticles UsingMolecules (Basel, Switzerland) · 2026Article
- One-Pot Green Synthesis of Amino Acid-Capped Gold Nanoparticles for Selective Sensing of Cyanide and Heavy Metals.ACS omega · 2026Article
- Synthesis of biocompatible gold nanoparticles for photothermal therapy by mineralization using peptides.RSC advances · 2025Article
- Biofabrication ofLife (Basel, Switzerland) · 2025Article
- Amino acid-modified nano-magnetite boosts okra [Abelmoschus esculentus (L.) Moench] yield and iron enrichment for improved nutrition.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Amino Compound-Synthesized Gold Nanoparticles for SARS-CoV-2 Antigen Delivery.Pharmaceutics · 2025Article
- Peptide-Based Inorganic Nanoparticles as Efficient Intracellular Delivery Systems.Pharmaceutics · 2025Review
- Monolayers of Amino Acid-Synthesized Gold Nanoparticles as SERS Substrates for Trace Chemical Sensing.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- A chronological study on formation mechanism of nesquehonite from nanoparticles to grown crystals and its application in nanoparticle synthesis.Scientific reports · 2025Article
- Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy.ChemPlusChem · 2025Review
- Novel platinum therapeutics induce rapid cancer cell death through triggering intracellular ROS storm.Biomaterials · 2025Article
- SERS of nitro group compounds for sensing of explosives.RSC advances · 2025Article
- Green Synthesis ofBiomolecules · 2024Article
- Engineered M13-Derived Bacteriophages Capable of Gold Nanoparticle Synthesis and Nanogold Manipulations.International journal of molecular sciences · 2024Article
- Prospect of Gold Nanoparticles in Pancreatic Cancer.Pharmaceutics · 2024Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amino acid-capped gold nanoparticles (AuNPs) are a promising tool for various applications, including therapeutics and diagnostics. Most often, amino acids are used to cap AuNPs synthesized with other reducing agents. However, only a few studies have been dedicated to using α-amino acids as reducing and capping agents in AuNPs synthesis. Hence, there are still several gaps in understanding their role in reducing gold salts. Here, we used 20 proteinogenic α-amino acids and one non-proteinogenic α-amino acid in analogy to sodium citrate as reducing and capping agents in synthesizing AuNPs using the Turkevich method. Only four of the twenty-one investigated amino acids have not yielded gold nanoparticles. The shape, size distribution, stability, and optical properties of synthesized nanoparticles were characterized by scanning electron microscopy, differential centrifugal sedimentation, the phase analysis light scattering technique, and UV-vis spectroscopy. The physicochemical characteristics of synthesized AuNPs varied with the amino acid used for the reduction. We proposed that in the initial stage of gold salts reduction most of the used α-amino acids behave similarly to citrate in the Turkevich method. However, their different physicochemical properties resulting from differences in their chemical structures significantly influence the outcomes of reactions.
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